Enzalutamide and Spinal cord compression - a phase IV clinical study of FDA data
Summary:
Spinal cord compression is reported as a side effect among people who take Enzalutamide (enzalutamide), especially for people who are male, 60+ old, have been taking the drug for 6 - 12 months also take Cabazitaxel, and have Metastases to bone.
The phase IV clinical study analyzes which people have Spinal cord compression when taking Enzalutamide. It is created by eHealthMe based on reports of 14,017 people who have side effects when taking Enzalutamide from the FDA, and is updated regularly.
What is Enzalutamide?
Enzalutamide has active ingredients of enzalutamide. eHealthMe is studying from 14,018 Enzalutamide users. Check the latest studies of Enzalutamide.
What is Spinal cord compression?
Spinal cord compression is found to be associated with 614 drugs and 599 conditions by eHealthMe. Check the latest studies of Spinal cord compression.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
14,017 people reported to have side effects when taking Enzalutamide.
Among them, 54 people (0.39%) have Spinal cord compression.

Among these 54 people:
How long have people been on Enzalutamide when they have Spinal cord compression? *
- < 1 month: 7.69 %
- 1 - 6 months: 23.08 %
- 6 - 12 months: 30.77 %
- 1 - 2 years: 15.38 %
- 2 - 5 years: 23.08 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Spinal cord compression when taking Enzalutamide? *
- female: 0.0 %
- male: 100 %
What is the age of people who have Spinal cord compression when taking Enzalutamide? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 0.0 %
- 50-59: 9.09 %
- 60+: 90.91 %
What are other drugs people take besides Enzalutamide? *
- Cabazitaxel: 8 people, 14.81%
- Zytiga: 6 people, 11.11%
- Xofigo: 6 people, 11.11%
- Xgeva: 6 people, 11.11%
- Zoledronic Acid: 4 people, 7.41%
- Docetaxel: 4 people, 7.41%
- Abiraterone Acetate: 4 people, 7.41%
- Zoladex: 4 people, 7.41%
- Lupron: 3 people, 5.56%
- Taxotere: 3 people, 5.56%
What are other side effects people have besides Spinal cord compression? *
- Malignant Neoplasm Progression (cancer tumour came back): 22 people, 40.74%
- Cervical Vertebral Fracture: 13 people, 24.07%
- Thoracic Vertebral Fracture: 12 people, 22.22%
- Weakness: 10 people, 18.52%
- Pain: 10 people, 18.52%
- Back Pain: 10 people, 18.52%
- Drug Ineffective: 9 people, 16.67%
- Nausea And Vomiting: 9 people, 16.67%
- Nausea (feeling of having an urge to vomit): 9 people, 16.67%
- Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 8 people, 14.81%
What are the existing conditions these people have? *
- Metastases To Bone (cancer spreads to bone): 20 people, 37.04%
- Prostate Cancer: 13 people, 24.07%
- Pain: 13 people, 24.07%
- Prostate Cancer Metastatic: 12 people, 22.22%
- Depression: 4 people, 7.41%
- Cancer Pain: 2 people, 3.70%
- Constipation: 2 people, 3.70%
- Urinary Tract Infection: 1 person, 1.85%
- Gastric Disorder (disease of stomach): 1 person, 1.85%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 1.85%
* Approximation only. Some reports may have incomplete information.
Do you take Enzalutamide and have Spinal cord compression?
- Check whether Spinal cord compression is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Enzalutamide:
- Enzalutamide (14,018 reports)
Spinal cord compression treatments and more:
- Spinal cord compression (5,324 reports)
How severe was Spinal cord compression and when was it recovered:
Expand to all the drugs that have ingredients of enzalutamide:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Enzalutamide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Spinal cord compression:
- Spinal cord compression (614 drugs)
Browse all the conditions that are associated with Spinal cord compression:
- Spinal cord compression (599 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on enzalutamide (the active ingredients of Enzalutamide) and Enzalutamide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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