Epclusa and Nausea - a phase IV clinical study of FDA data

Summary:

Nausea is reported as a side effect among people who take Epclusa (sofosbuvir; velpatasvir), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Zofran, and have Hepatitis c.

The phase IV clinical study analyzes which people have Nausea when taking Epclusa. It is created by eHealthMe based on reports of 12,085 people who have side effects when taking Epclusa from the FDA, and is updated regularly.

What is Epclusa?

Epclusa has active ingredients of sofosbuvir; velpatasvir. eHealthMe is studying from 12,120 Epclusa users. Check the latest studies of Epclusa.

What is Nausea?

Nausea (feeling of having an urge to vomit) is found to be associated with 3,877 drugs and 5,632 conditions by eHealthMe. Check the latest studies of Nausea.

On Jul, 08, 2026

12,085 people reported to have side effects when taking Epclusa.
Among them, 1,143 people (9.46%) have Nausea.

Among these 1,143 people:

* Approximation only. Some reports may have incomplete information.

Do you take Epclusa and have Nausea?

- Check whether Nausea is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Epclusa:

Epclusa (12,120 reports)

Nausea treatments and more:

Nausea (962,089 reports)

How severe was Nausea and when was it recovered:

Nausea in Epclusa

Expand to all the drugs that have ingredients of sofosbuvir; velpatasvir:

Nausea and drugs with ingredients of sofosbuvir; velpatasvir

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Epclusa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nausea:

Nausea (3,877 drugs)

Browse all the conditions that are associated with Nausea:

Nausea (5,632 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sofosbuvir; velpatasvir (the active ingredients of Epclusa) and Epclusa (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.