Ephedrine and Intervertebral disc protrusion - a phase IV clinical study of FDA data

Summary:

Intervertebral disc protrusion is reported as a side effect among people who take Ephedrine (ephedra), especially for people who are male, 60+ old, also take Xanax, and have High blood pressure.

The phase IV clinical study analyzes which people have Intervertebral disc protrusion when taking Ephedrine. It is created by eHealthMe based on reports of 1,683 people who have side effects when taking Ephedrine from the FDA, and is updated regularly.

What is Ephedrine?

Ephedrine has active ingredients of ephedra. It is often used in weight loss. eHealthMe is studying from 1,763 Ephedrine users. Check the latest studies of Ephedrine.

What is Intervertebral disc protrusion?

Intervertebral disc protrusion (spinal disc protrusion) is found to be associated with 1,531 drugs and 1,306 conditions by eHealthMe. Check the latest studies of Intervertebral disc protrusion.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

1,683 people reported to have side effects when taking Ephedrine.
Among them, 30 people (1.78%) have Intervertebral disc protrusion.

Could Ephedrine cause Intervertebral disc protrusion?

Among these 30 people:

What is the gender of people who have Intervertebral disc protrusion when taking Ephedrine? *

female: 36.67 %
male: 63.33 %

What is the age of people who have Intervertebral disc protrusion when taking Ephedrine? *

What are other drugs people take besides Ephedrine? *

What are other side effects people have besides Intervertebral disc protrusion? *

Spinal Osteoarthritis (joint cartilage loss in spine): 28 people, 93.33%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 27 people, 90.00%
Gingival Pain (gum pain): 26 people, 86.67%
Chest Pain: 26 people, 86.67%
Osteonecrosis Of Jaw (death of bone of jaw): 25 people, 83.33%
Anaemia (lack of blood): 21 people, 70.00%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 21 people, 70.00%
Loose Tooth: 21 people, 70.00%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 21 people, 70.00%
High Blood Pressure: 19 people, 63.33%

What are the existing conditions these people have? *

High Blood Cholesterol: 11 people, 36.67%
Seasonal Allergy (allergic condition due to certain season): 11 people, 36.67%
Blood Triglycerides Decreased: 11 people, 36.67%
Diarrhea: 11 people, 36.67%
Multiple Myeloma (cancer of the plasma cells): 11 people, 36.67%
Mood Swings (an extreme or rapid change in mood): 11 people, 36.67%
Joint Pain: 11 people, 36.67%
Seborrhoeic Dermatitis (a common, inflammatory skin condition that causes flaky, white to yellowish scales to form on oily areas such as the scalp): 11 people, 36.67%
Fluid Retention (an abnormal accumulation of fluid in the blood): 11 people, 36.67%
High Blood Pressure: 11 people, 36.67%

* Approximation only. Some reports may have incomplete information.

Do you take Ephedrine and have Intervertebral disc protrusion?

- Check whether Intervertebral disc protrusion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ephedrine:

Ephedrine (1,763 reports)

Browse all side effects of Ephedrine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Intervertebral disc protrusion:

Intervertebral disc protrusion (1,531 drugs)

Browse all the conditions that are associated with Intervertebral disc protrusion:

Intervertebral disc protrusion (1,306 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ephedra (the active ingredients of Ephedrine) and Ephedrine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.