Epidiolex and Appetite - increased - a phase IV clinical study of FDA data

Summary:

Appetite - increased is reported as a side effect among people who take Epidiolex (cannabidiol), especially for people who are male, 2-9 old, have been taking the drug for < 1 month also take Onfi, and have Lennox-gastaut syndrome.

The phase IV clinical study analyzes which people have Appetite - increased when taking Epidiolex. It is created by eHealthMe based on reports of 18,738 people who have side effects when taking Epidiolex from the FDA, and is updated regularly.

What is Epidiolex?

Epidiolex has active ingredients of cannabidiol. eHealthMe is studying from 18,763 Epidiolex users. Check the latest studies of Epidiolex.

What is Appetite - increased?

Appetite - increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires) is found to be associated with 1,571 drugs and 2,029 conditions by eHealthMe. Check the latest studies of Appetite - increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 18, 2026

18,738 people reported to have side effects when taking Epidiolex.
Among them, 69 people (0.37%) have Appetite - increased.

Could Epidiolex cause Appetite - increased?

Among these 69 people:

How long have people been on Epidiolex when they have Appetite - increased? *

What is the gender of people who have Appetite - increased when taking Epidiolex? *

female: 28.57 %
male: 71.43 %

What is the age of people who have Appetite - increased when taking Epidiolex? *

What are other drugs people take besides Epidiolex? *

What are other side effects people have besides Appetite - increased? *

Weight Increased: 34 people, 49.28%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 14 people, 20.29%
Aggression: 9 people, 13.04%
Fatigue (feeling of tiredness): 5 people, 7.25%
Stress And Anxiety: 4 people, 5.80%
Drowsiness: 4 people, 5.80%
The Flu (the flu is caused by an influenza virus): 4 people, 5.80%
Nausea And Vomiting: 3 people, 4.35%
Rhinovirus Infection: 3 people, 4.35%
Diarrhea: 3 people, 4.35%

What are the existing conditions these people have? *

Lennox-Gastaut Syndrome (epilepsy characterized by frequent seizures and different seizure types): 39 people, 56.52%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 21 people, 30.43%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 9 people, 13.04%
Partial Seizures (seizures which affect only a part of the brain at onset): 6 people, 8.70%
Sleep Disorder: 2 people, 2.90%
Idiopathic Generalised Epilepsy (epileptic disorders that are believed to have a strong underlying genetic basis): 2 people, 2.90%
Ovarian Cancer (cancer of ovary): 1 person, 1.45%
Fallopian Tube Cancer (cancer of fallopian tube): 1 person, 1.45%
Hypersensitivity: 1 person, 1.45%
Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract): 1 person, 1.45%

* Approximation only. Some reports may have incomplete information.

Do you take Epidiolex and have Appetite - increased?

- Check whether Appetite - increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Epidiolex:

Epidiolex (18,763 reports)

Browse all side effects of Epidiolex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Appetite - increased:

Appetite - increased (1,571 drugs)

Browse all the conditions that are associated with Appetite - increased:

Appetite - increased (2,029 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cannabidiol (the active ingredients of Epidiolex) and Epidiolex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.