Epival and Lightheadedness - a phase IV clinical study of FDA data

Summary:

Lightheadedness is reported as a side effect among people who take Epival (divalproex sodium), especially for people who are female, 60+ old, also take Clozaril, and have Ulcerative colitis.

The phase IV clinical study analyzes which people have Lightheadedness when taking Epival. It is created by eHealthMe based on reports of 968 people who have side effects when taking Epival from the FDA, and is updated regularly.

What is Epival?

Epival has active ingredients of divalproex sodium. It is often used in epilepsy. eHealthMe is studying from 1,088 Epival users. Check the latest studies of Epival.

What is Lightheadedness?

Lightheadedness (a common and often unpleasant sensation of dizziness and/or feeling that one may be about to faint) is found to be associated with 3,966 drugs and 5,781 conditions by eHealthMe. Check the latest studies of Lightheadedness.

On Jun, 25, 2026

968 people reported to have side effects when taking Epival.
Among them, 54 people (5.58%) have Lightheadedness.

Among these 54 people:

What is the gender of people who have Lightheadedness when taking Epival? *

female: 66.67 %
male: 33.33 %

What is the age of people who have Lightheadedness when taking Epival? *

What are other drugs people take besides Epival? *

What are other side effects people have besides Lightheadedness? *

Headache (pain in head): 25 people, 46.30%
Nausea (feeling of having an urge to vomit): 18 people, 33.33%
Fatigue (feeling of tiredness): 15 people, 27.78%
Weakness: 14 people, 25.93%
Diarrhea: 12 people, 22.22%
Nausea And Vomiting: 12 people, 22.22%
Abdominal Discomfort: 11 people, 20.37%
Fall: 11 people, 20.37%
Stress And Anxiety: 10 people, 18.52%
Gait Disturbance: 9 people, 16.67%

What are the existing conditions these people have? *

Uveitis (inflammation of the uvea): 8 people, 14.81%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 8 people, 14.81%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 5 people, 9.26%
Indigestion: 5 people, 9.26%
Psychotic Disorder: 5 people, 9.26%
Type 2 Diabetes: 4 people, 7.41%
Neoplasm Malignant (cancer tumour): 4 people, 7.41%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 3 people, 5.56%
Sleep Disorder: 3 people, 5.56%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 3.70%

* Approximation only. Some reports may have incomplete information.

Do you take Epival and have Lightheadedness?

- Check whether Lightheadedness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Epival:

Epival (1,088 reports)

Lightheadedness treatments and more:

Lightheadedness (613,960 reports)

Browse all side effects of Epival:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Lightheadedness:

Lightheadedness (3,966 drugs)

Browse all the conditions that are associated with Lightheadedness:

Lightheadedness (5,781 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on divalproex sodium (the active ingredients of Epival) and Epival (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.