Epival and Niddm - a phase IV clinical study of FDA data

Summary:

Niddm is reported as a side effect among people who take Epival (divalproex sodium), especially for people who are male, 50-59 old, also take Zyprexa, and have Bipolar i disorder.

The phase IV clinical study analyzes which people have Niddm when taking Epival. It is created by eHealthMe based on reports of 968 people who have side effects when taking Epival from the FDA, and is updated regularly.

What is Epival?

Epival has active ingredients of divalproex sodium. It is often used in epilepsy. eHealthMe is studying from 1,088 Epival users. Check the latest studies of Epival.

What is Niddm?

Niddm is found to be associated with 2,382 drugs and 2,352 conditions by eHealthMe. Check the latest studies of Niddm.



On Jul, 21, 2026

968 people reported to have side effects when taking Epival.
Among them, 9 people (0.93%) have Niddm.

Could Epival cause Niddm?

Among these 9 people:

What is the gender of people who have Niddm when taking Epival? *

  • female: 44.44 %
  • male: 55.56 %

What is the age of people who have Niddm when taking Epival? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 11.11 %
  • 30-39: 0.0 %
  • 40-49: 11.11 %
  • 50-59: 44.44 %
  • 60+: 33.33 %

What are other drugs people take besides Epival? *

  1. Zyprexa: 7 people, 77.78%
  2. Risperdal: 4 people, 44.44%
  3. Seroquel: 4 people, 44.44%
  4. Lipitor: 3 people, 33.33%
  5. Bricanyl: 3 people, 33.33%
  6. Lamictal: 3 people, 33.33%
  7. Diovan: 3 people, 33.33%
  8. Crestor: 3 people, 33.33%
  9. Clozaril: 3 people, 33.33%
  10. Celebrex: 3 people, 33.33%

What are other side effects people have besides Niddm? *

  1. High Blood Pressure: 6 people, 66.67%
  2. Hypertriglyceridaemia (excess of triglycerides in the blood): 3 people, 33.33%
  3. Weight Increased: 3 people, 33.33%
  4. Leukocytosis (increased white blood cells): 3 people, 33.33%
  5. High Blood Cholesterol: 3 people, 33.33%
  6. Metabolic Syndrome (a combination of the medical disorders that, when occurring together, increase the risk of developing cardiovascular disease): 3 people, 33.33%
  7. Nephropathy (damage to or disease of a kidney): 3 people, 33.33%
  8. Neutrophilia: 3 people, 33.33%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 33.33%
  10. Gastritis (inflammation of stomach): 3 people, 33.33%

What are the existing conditions these people have? *

  1. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 22.22%
  2. Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 2 people, 22.22%
  3. High Blood Pressure: 1 person, 11.11%
  4. Diabetes: 1 person, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Epival and have Niddm?

- Check whether Niddm is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Epival:

Niddm treatments and more:

  • Niddm (391,582 reports)

How severe was Niddm and when was it recovered:

Expand to all the drugs that have ingredients of divalproex sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Epival:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Niddm:

Browse all the conditions that are associated with Niddm:

  • Niddm (2,352 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on divalproex sodium (the active ingredients of Epival) and Epival (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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