Epivir and Oedema - a phase IV clinical study of FDA data

Summary:

Oedema is reported as a side effect among people who take Epivir (lamivudine), especially for people who are male, 40-49 old, have been taking the drug for 2 - 5 years also take Zerit, and have Acquired immunodeficiency syndrome.

The phase IV clinical study analyzes which people have Oedema when taking Epivir. It is created by eHealthMe based on reports of 16,823 people who have side effects when taking Epivir from the FDA, and is updated regularly.

What is Epivir?

Epivir has active ingredients of lamivudine. It is often used in hiv infection. eHealthMe is studying from 16,870 Epivir users. Check the latest studies of Epivir.

What is Oedema?

Oedema (fluid collection in tissue) is found to be associated with 2,200 drugs and 2,311 conditions by eHealthMe. Check the latest studies of Oedema.



On Jul, 20, 2026

16,823 people reported to have side effects when taking Epivir.
Among them, 89 people (0.53%) have Oedema.

Could Epivir cause Oedema?

Among these 89 people:

How long have people been on Epivir when they have Oedema? *

  • < 1 month: 21.43 %
  • 1 - 6 months: 28.57 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 7.14 %
  • 2 - 5 years: 42.86 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Oedema when taking Epivir? *

  • female: 29.55 %
  • male: 70.45 %

What is the age of people who have Oedema when taking Epivir? *

  • 0-1: 0.0 %
  • 2-9: 2.56 %
  • 10-19: 1.28 %
  • 20-29: 5.13 %
  • 30-39: 29.49 %
  • 40-49: 41.03 %
  • 50-59: 12.82 %
  • 60+: 7.69 %

What are other drugs people take besides Epivir? *

  1. Zerit: 40 people, 44.94%
  2. Viread: 15 people, 16.85%
  3. Bactrim: 14 people, 15.73%
  4. Videx: 13 people, 14.61%
  5. Crixivan: 13 people, 14.61%
  6. Sustiva: 12 people, 13.48%
  7. Viracept: 12 people, 13.48%
  8. Retrovir: 11 people, 12.36%
  9. Kaletra: 11 people, 12.36%
  10. Ziagen: 10 people, 11.24%

What are other side effects people have besides Oedema? *

  1. Fever: 31 people, 34.83%
  2. Lactic Acidosis (low ph in body tissues): 16 people, 17.98%
  3. Ascites (accumulation of fluid in the abdominal cavity): 14 people, 15.73%
  4. Fatigue (feeling of tiredness): 12 people, 13.48%
  5. Weight Increased: 11 people, 12.36%
  6. Muscle Aches (muscle pain): 11 people, 12.36%
  7. Acute Kidney Failure: 10 people, 11.24%
  8. Rashes (redness): 10 people, 11.24%
  9. Hepatomegaly (abnormal enlargement of the liver): 9 people, 10.11%
  10. Hypotension (abnormally low blood pressure): 8 people, 8.99%

What are the existing conditions these people have? *

  1. Acquired Immunodeficiency Syndrome (disease of the human immune system caused by the human immunodeficiency virus (hiv)): 3 people, 3.37%
  2. Mitochondrial Toxicity (a condition in which the mitochondria of a body's cells become damaged or decline significantly in number;): 2 people, 2.25%
  3. Cytomegalovirus Infection: 2 people, 2.25%
  4. Diabetes: 2 people, 2.25%
  5. Diarrhea: 2 people, 2.25%
  6. Folliculitis (infection of hair root): 2 people, 2.25%
  7. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 2 people, 2.25%
  8. Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking): 2 people, 2.25%
  9. Swallowing Difficulty: 2 people, 2.25%
  10. Oral Candidiasis (fungal infection of mouth): 2 people, 2.25%

* Approximation only. Some reports may have incomplete information.

Do you take Epivir and have Oedema?

- Check whether Oedema is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Epivir:

Oedema treatments and more:

How severe was Oedema and when was it recovered:

Expand to all the drugs that have ingredients of lamivudine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Epivir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Oedema:

Browse all the conditions that are associated with Oedema:


How the study uses the data?

The study uses data from the FDA. It is based on lamivudine (the active ingredients of Epivir) and Epivir (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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