Eplerenone and Peptic ulcer aggravated - a phase IV clinical study of FDA data

Summary:

Peptic ulcer aggravated is reported as a side effect among people who take Eplerenone (eplerenone), especially for people who are male, 60+ old, also take Entresto, and have Depression.

The phase IV clinical study analyzes which people have Peptic ulcer aggravated when taking Eplerenone. It is created by eHealthMe based on reports of 9,846 people who have side effects when taking Eplerenone from the FDA, and is updated regularly.

What is Eplerenone?

Eplerenone has active ingredients of eplerenone. It is often used in high blood pressure. eHealthMe is studying from 9,979 Eplerenone users. Check the latest studies of Eplerenone.

What is Peptic ulcer aggravated?

Peptic ulcer aggravated is found to be associated with 1,491 drugs and 545 conditions by eHealthMe. Check the latest studies of Peptic ulcer aggravated.

On Jul, 13, 2026

9,846 people reported to have side effects when taking Eplerenone.
Among them, 27 people (0.27%) have Peptic ulcer aggravated.

Could Eplerenone cause Peptic ulcer aggravated?

Among these 27 people:

What is the gender of people who have Peptic ulcer aggravated when taking Eplerenone? *

female: 41.67 %
male: 58.33 %

What is the age of people who have Peptic ulcer aggravated when taking Eplerenone? *

What are other drugs people take besides Eplerenone? *

Furosemide: 12 people, 44.44%
Entresto: 12 people, 44.44%
Allopurinol: 8 people, 29.63%
Metformin: 8 people, 29.63%
Pantoprazole: 8 people, 29.63%
Carvedilol: 8 people, 29.63%
Isosorbide Mononitrate: 7 people, 25.93%
Hydrochlorothiazide: 7 people, 25.93%
Ezetimibe: 7 people, 25.93%
Clopidogrel: 7 people, 25.93%

What are other side effects people have besides Peptic ulcer aggravated? *

Disease Progression: 7 people, 25.93%
Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 7 people, 25.93%
Acute Myocardial Infarction (acute heart attack): 7 people, 25.93%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 7 people, 25.93%
High Blood Cholesterol: 7 people, 25.93%
Cardiac Failure: 7 people, 25.93%
Arteriosclerosis Coronary Artery (thickening and hardening of arteries- coronary artery): 7 people, 25.93%
Nephrosclerosis (hardening of the kidney due to renovascular disease): 7 people, 25.93%
Renal Disorder (kidney disease): 6 people, 22.22%
Duodenitis (inflammation of the duodenum): 6 people, 22.22%

What are the existing conditions these people have? *

Depression: 4 people, 14.81%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 11.11%
Immunodeficiency Common Variable: 3 people, 11.11%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 3 people, 11.11%
Thyroid Cancer: 3 people, 11.11%
Endometrial Cancer: 2 people, 7.41%
High Blood Cholesterol: 1 person, 3.70%
Heart Attack: 1 person, 3.70%
Gastric Ulcer Haemorrhage (bleeding ulcer of stomach): 1 person, 3.70%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 1 person, 3.70%

* Approximation only. Some reports may have incomplete information.

Do you take Eplerenone and have Peptic ulcer aggravated?

- Check whether Peptic ulcer aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Eplerenone:

Eplerenone (9,979 reports)

Browse all side effects of Eplerenone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Peptic ulcer aggravated:

Peptic ulcer aggravated (1,491 drugs)

Browse all the conditions that are associated with Peptic ulcer aggravated:

Peptic ulcer aggravated (545 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on eplerenone (the active ingredients of Eplerenone) and Eplerenone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.