Erivedge and Joint stiffness - a phase IV clinical study of FDA data

Summary:

Joint stiffness is reported as a side effect among people who take Erivedge (vismodegib), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Amlodipine, and have Basal cell carcinoma.

The phase IV clinical study analyzes which people have Joint stiffness when taking Erivedge. It is created by eHealthMe based on reports of 7,786 people who have side effects when taking Erivedge from the FDA, and is updated regularly.

What is Erivedge?

Erivedge has active ingredients of vismodegib. eHealthMe is studying from 7,787 Erivedge users. Check the latest studies of Erivedge.

What is Joint stiffness?

Joint stiffness is found to be associated with 1,301 drugs and 1,341 conditions by eHealthMe. Check the latest studies of Joint stiffness.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

7,786 people reported to have side effects when taking Erivedge.
Among them, 15 people (0.19%) have Joint stiffness.

Among these 15 people:

How long have people been on Erivedge when they have Joint stiffness? *

What is the gender of people who have Joint stiffness when taking Erivedge? *

female: 26.67 %
male: 73.33 %

What is the age of people who have Joint stiffness when taking Erivedge? *

What are other drugs people take besides Erivedge? *

What are other side effects people have besides Joint stiffness? *

Muscle Spasms (muscle contraction): 10 people, 66.67%
Joint Pain: 9 people, 60.00%
Back Pain: 7 people, 46.67%
Weakness: 7 people, 46.67%
Abdominal Pain Upper: 6 people, 40.00%
Constipation: 6 people, 40.00%
Fatigue (feeling of tiredness): 6 people, 40.00%
Pain In Extremity: 6 people, 40.00%
Hypoaesthesia (reduced sense of touch or sensation): 5 people, 33.33%
Nausea (feeling of having an urge to vomit): 4 people, 26.67%

What are the existing conditions these people have? *

Basal Cell Carcinoma (a skin cancer, it rarely metastasizes or kills): 14 people, 93.33%
Skin Cancer: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Erivedge and have Joint stiffness?

- Check whether Joint stiffness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Erivedge:

Erivedge (7,787 reports)

Joint stiffness treatments and more:

Joint stiffness (33,165 reports)

Browse all side effects of Erivedge:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Joint stiffness:

Joint stiffness (1,301 drugs)

Browse all the conditions that are associated with Joint stiffness:

Joint stiffness (1,341 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on vismodegib (the active ingredients of Erivedge) and Erivedge (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.