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Erleada and Constipation - a phase IV clinical study of FDA data

Summary:

Constipation is reported as a side effect among people who take Erleada (apalutamide), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Eligard, and have Prostate cancer.

The phase IV clinical study analyzes which people have Constipation when taking Erleada. It is created by eHealthMe based on reports of 7,515 people who have side effects when taking Erleada from the FDA, and is updated regularly.

What is Erleada?

Erleada has active ingredients of apalutamide. eHealthMe is studying from 7,519 Erleada users. Check the latest studies of Erleada.

What is Constipation?

Constipation is found to be associated with 3,004 drugs and 4,611 conditions by eHealthMe. Check the latest studies of Constipation.

On Jul, 13, 2026

7,515 people reported to have side effects when taking Erleada.
Among them, 79 people (1.05%) have Constipation.

Could Erleada cause Constipation?

Among these 79 people:

How long have people been on Erleada when they have Constipation? *

  • < 1 month: 70 %
  • 1 - 6 months: 30 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Constipation when taking Erleada? *

  • female: 0.0 %
  • male: 100 %

What is the age of people who have Constipation when taking Erleada? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 1.82 %
  • 60+: 98.18 %

What are other drugs people take besides Erleada? *

  1. Eligard: 15 people, 18.99%
  2. Lupron: 4 people, 5.06%
  3. Orgovyx: 4 people, 5.06%
  4. Vitamin D3: 4 people, 5.06%
  5. Tamsulosin: 4 people, 5.06%
  6. Xtandi: 4 people, 5.06%
  7. Vitamins: 3 people, 3.80%
  8. Metformin: 3 people, 3.80%
  9. Aspirin: 3 people, 3.80%
  10. Coumadin: 2 people, 2.53%

What are other side effects people have besides Constipation? *

  1. Fatigue (feeling of tiredness): 27 people, 34.18%
  2. Hot Flush (sudden feelings of heat): 22 people, 27.85%
  3. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 17 people, 21.52%
  4. Injection Site Pain: 12 people, 15.19%
  5. Weakness: 11 people, 13.92%
  6. Joint Pain: 11 people, 13.92%
  7. Weight Decreased: 10 people, 12.66%
  8. Pain: 9 people, 11.39%
  9. Back Pain: 8 people, 10.13%
  10. Diarrhea: 8 people, 10.13%

What are the existing conditions these people have? *

  1. Prostate Cancer: 42 people, 53.16%
  2. Prostate Cancer Metastatic: 8 people, 10.13%
  3. Renal Cell Carcinoma (a kidney cancer): 1 person, 1.27%
  4. Pain: 1 person, 1.27%
  5. Neoplasm Prostate (tumour of prostate): 1 person, 1.27%
  6. High Blood Cholesterol: 1 person, 1.27%
  7. Haematuria (presence of blood in urine): 1 person, 1.27%
  8. Gout (uric acid crystals building up in the body): 1 person, 1.27%
  9. Diabetes: 1 person, 1.27%

* Approximation only. Some reports may have incomplete information.

Do you take Erleada and have Constipation?

- Check whether Constipation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Erleada:

Constipation treatments and more:

How severe was Constipation and when was it recovered:

Expand to all the drugs that have ingredients of apalutamide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Erleada:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Constipation:

Browse all the conditions that are associated with Constipation:

How the study uses the data?

The study uses data from the FDA. It is based on apalutamide (the active ingredients of Erleada) and Erleada (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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