Erwinaze and Hypersensitivity - a phase IV clinical study of FDA data

Summary:

Hypersensitivity is reported as a side effect among people who take Erwinaze (asparaginase erwinia chrysanthemi), especially for people who are male, 2-9 old, have been taking the drug for < 1 month also take Benadryl, and have Acute lymphocytic leukemia (all).

The phase IV clinical study analyzes which people have Hypersensitivity when taking Erwinaze. It is created by eHealthMe based on reports of 274 people who have side effects when taking Erwinaze from the FDA, and is updated regularly.

What is Erwinaze?

Erwinaze has active ingredients of asparaginase erwinia chrysanthemi. eHealthMe is studying from 275 Erwinaze users. Check the latest studies of Erwinaze.

What is Hypersensitivity?

Hypersensitivity is found to be associated with 2,750 drugs and 2,915 conditions by eHealthMe. Check the latest studies of Hypersensitivity.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

274 people reported to have side effects when taking Erwinaze.
Among them, 43 people (15.69%) have Hypersensitivity.

Among these 43 people:

How long have people been on Erwinaze when they have Hypersensitivity? *

What is the gender of people who have Hypersensitivity when taking Erwinaze? *

female: 50 %
male: 50 %

What is the age of people who have Hypersensitivity when taking Erwinaze? *

What are other drugs people take besides Erwinaze? *

What are other side effects people have besides Hypersensitivity? *

Nausea And Vomiting: 2 people, 4.65%
Nausea (feeling of having an urge to vomit): 2 people, 4.65%
Chills (felling of cold): 2 people, 4.65%
Skin Discoloration: 1 person, 2.33%
Skin Blushing/flushing (a sudden reddening of the face, neck): 1 person, 2.33%
Rashes (redness): 1 person, 2.33%
Pancreatitis (inflammation of pancreas): 1 person, 2.33%
Mental Status Changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 1 person, 2.33%
Malaise (a feeling of general discomfort or uneasiness): 1 person, 2.33%
Hyperammonaemia: 1 person, 2.33%

What are the existing conditions these people have? *

Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 20 people, 46.51%
B-Cell Type Acute Leukaemia (cancer of the white blood cells): 3 people, 6.98%
B Precursor Type Acute Leukaemia (lymphoid cancer): 2 people, 4.65%
Leukaemia (blood or bone marrow cancer): 1 person, 2.33%
Acute Biphenotypic Leukaemia (leukaemia where the lineage is of both lymphoid and myeloid origin): 1 person, 2.33%

* Approximation only. Some reports may have incomplete information.

Do you take Erwinaze and have Hypersensitivity?

- Check whether Hypersensitivity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Erwinaze:

Erwinaze (275 reports)

Hypersensitivity treatments and more:

Hypersensitivity (272,618 reports)

How severe was Hypersensitivity and when was it recovered:

Hypersensitivity in Erwinaze

Expand to all the drugs that have ingredients of asparaginase erwinia chrysanthemi:

Hypersensitivity and drugs with ingredients of asparaginase erwinia chrysanthemi (65 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Erwinaze:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypersensitivity:

Hypersensitivity (2,750 drugs)

Browse all the conditions that are associated with Hypersensitivity:

Hypersensitivity (2,915 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on asparaginase erwinia chrysanthemi (the active ingredients of Erwinaze) and Erwinaze (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.