Esgic and Hyperhidrosis - a phase IV clinical study of FDA data

Summary:

Hyperhidrosis is reported as a side effect among people who take Esgic (acetaminophen; butalbital; caffeine), especially for people who are female, 40-49 old, also take Norco, and have Pain.

The phase IV clinical study analyzes which people have Hyperhidrosis when taking Esgic. It is created by eHealthMe based on reports of 813 people who have side effects when taking Esgic from the FDA, and is updated regularly.

What is Esgic?

Esgic has active ingredients of acetaminophen; butalbital; caffeine. It is often used in migraine. eHealthMe is studying from 882 Esgic users. Check the latest studies of Esgic.

What is Hyperhidrosis?

Hyperhidrosis (abnormally increased sweating) is found to be associated with 2,551 drugs and 3,547 conditions by eHealthMe. Check the latest studies of Hyperhidrosis.

On Jul, 13, 2026

813 people reported to have side effects when taking Esgic.
Among them, 29 people (3.57%) have Hyperhidrosis.

Among these 29 people:

What is the gender of people who have Hyperhidrosis when taking Esgic? *

female: 85.71 %
male: 14.29 %

What is the age of people who have Hyperhidrosis when taking Esgic? *

What are other drugs people take besides Esgic? *

What are other side effects people have besides Hyperhidrosis? *

Fatigue (feeling of tiredness): 18 people, 62.07%
Joint Pain: 16 people, 55.17%
Back Pain: 14 people, 48.28%
Fever: 14 people, 48.28%
Cough: 13 people, 44.83%
Depression: 13 people, 44.83%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 13 people, 44.83%
Peripheral Swelling: 13 people, 44.83%
Oedema (fluid collection in tissue): 12 people, 41.38%
Increased Tendency To Bruise (increased tendency to injure the underlying soft tissue or bone): 12 people, 41.38%

What are the existing conditions these people have? *

Pain: 16 people, 55.17%
High Blood Pressure: 12 people, 41.38%
Allergic Rhinitis: 11 people, 37.93%
Sleep Disorder: 11 people, 37.93%
Sleep Apnea Syndrome: 11 people, 37.93%
Rickets (softening of bones): 11 people, 37.93%
Hypokalemia (low potassium): 11 people, 37.93%
Prostate Cancer Metastatic: 3 people, 10.34%
Depression: 3 people, 10.34%
Stress And Anxiety: 3 people, 10.34%

* Approximation only. Some reports may have incomplete information.

Do you take Esgic and have Hyperhidrosis?

- Check whether Hyperhidrosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Esgic:

Esgic (882 reports)

Hyperhidrosis treatments and more:

Hyperhidrosis (147,206 reports)

How severe was Hyperhidrosis and when was it recovered:

Hyperhidrosis in Esgic

Expand to all the drugs that have ingredients of acetaminophen; butalbital; caffeine:

Hyperhidrosis and drugs with ingredients of acetaminophen; butalbital; caffeine (812 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Esgic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperhidrosis:

Hyperhidrosis (2,551 drugs)

Browse all the conditions that are associated with Hyperhidrosis:

Hyperhidrosis (3,547 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; butalbital; caffeine (the active ingredients of Esgic) and Esgic (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.