Esgic and Rashes - a phase IV clinical study of FDA data

Summary:

Rashes is reported as a side effect among people who take Esgic (acetaminophen; butalbital; caffeine), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Ativan, and have Pain.

The phase IV clinical study analyzes which people have Rashes when taking Esgic. It is created by eHealthMe based on reports of 813 people who have side effects when taking Esgic from the FDA, and is updated regularly.

What is Esgic?

Esgic has active ingredients of acetaminophen; butalbital; caffeine. It is often used in migraine. eHealthMe is studying from 882 Esgic users. Check the latest studies of Esgic.

What is Rashes?

Rashes (redness) is found to be associated with 3,716 drugs and 6,216 conditions by eHealthMe. Check the latest studies of Rashes.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

813 people reported to have side effects when taking Esgic.
Among them, 30 people (3.69%) have Rashes.

Among these 30 people:

How long have people been on Esgic when they have Rashes? *

What is the gender of people who have Rashes when taking Esgic? *

female: 86.67 %
male: 13.33 %

What is the age of people who have Rashes when taking Esgic? *

What are other drugs people take besides Esgic? *

What are other side effects people have besides Rashes? *

Nausea And Vomiting: 13 people, 43.33%
Nausea (feeling of having an urge to vomit): 11 people, 36.67%
Stress And Anxiety: 10 people, 33.33%
Fatigue (feeling of tiredness): 9 people, 30.00%
Malaise (a feeling of general discomfort or uneasiness): 9 people, 30.00%
Drug Ineffective: 7 people, 23.33%
Itching: 7 people, 23.33%
Fall: 6 people, 20.00%
Infusion Related Reaction: 5 people, 16.67%
Feeling Abnormal: 5 people, 16.67%

What are the existing conditions these people have? *

Pain: 8 people, 26.67%
Stress And Anxiety: 6 people, 20.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 16.67%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 16.67%
Nausea (feeling of having an urge to vomit): 4 people, 13.33%
Irritable Bowel Syndrome: 4 people, 13.33%
Breakthrough Pain: 3 people, 10.00%
Glaucoma (increased fluid pressure in the eye with vision loss): 3 people, 10.00%
Immunodeficiency Common Variable: 2 people, 6.67%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Esgic and have Rashes?

- Check whether Rashes is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Esgic:

Esgic (882 reports)

Rashes treatments and more:

Rashes (702,909 reports)

How severe was Rashes and when was it recovered:

Rashes in Esgic

Expand to all the drugs that have ingredients of acetaminophen; butalbital; caffeine:

Rashes and drugs with ingredients of acetaminophen; butalbital; caffeine (3,340 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Esgic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rashes:

Rashes (3,716 drugs)

Browse all the conditions that are associated with Rashes:

Rashes (6,216 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; butalbital; caffeine (the active ingredients of Esgic) and Esgic (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.