Esidrix and Gamma-glutamyltransferase increased - a phase IV clinical study of FDA data

Summary:

Gamma-glutamyltransferase increased is reported as a side effect among people who take Esidrix (hydrochlorothiazide), especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years also take Aspirin, and have Type 2 diabetes.

The phase IV clinical study analyzes which people have Gamma-glutamyltransferase increased when taking Esidrix. It is created by eHealthMe based on reports of 1,831 people who have side effects when taking Esidrix from the FDA, and is updated regularly.

What is Esidrix?

Esidrix has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 1,846 Esidrix users. Check the latest studies of Esidrix.

What is Gamma-glutamyltransferase increased?

Gamma-glutamyltransferase increased is found to be associated with 1,345 drugs and 2,167 conditions by eHealthMe. Check the latest studies of Gamma-glutamyltransferase increased.

On Aug, 04, 2026

1,831 people reported to have side effects when taking Esidrix.
Among them, 37 people (2.02%) have Gamma-glutamyltransferase increased.

Could Esidrix cause Gamma-glutamyltransferase increased?

Among these 37 people:

How long have people been on Esidrix when they have Gamma-glutamyltransferase increased? *

What is the gender of people who have Gamma-glutamyltransferase increased when taking Esidrix? *

female: 37.84 %
male: 62.16 %

What is the age of people who have Gamma-glutamyltransferase increased when taking Esidrix? *

What are other drugs people take besides Esidrix? *

What are other side effects people have besides Gamma-glutamyltransferase increased? *

Blood Alkaline Phosphatase Increased: 14 people, 37.84%
Aspartate Aminotransferase Increased: 11 people, 29.73%
Alanine Aminotransferase Increased: 10 people, 27.03%
C-Reactive Protein Increased: 7 people, 18.92%
Haemoglobin Decreased: 6 people, 16.22%
Acute Kidney Failure: 5 people, 13.51%
Fever: 5 people, 13.51%
Blood Creatinine Increased: 5 people, 13.51%
Erythema Multiforme (a type of hypersensitivity reaction): 5 people, 13.51%
Blood Chloride Decreased: 4 people, 10.81%

What are the existing conditions these people have? *

Cardiac Failure: 3 people, 8.11%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 8.11%
Type 2 Diabetes: 3 people, 8.11%
Vitamin B Complex Deficiency: 2 people, 5.41%
Iron Deficiency: 2 people, 5.41%
Chronic Kidney Disease: 2 people, 5.41%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 5.41%
Constipation: 2 people, 5.41%
Depression: 2 people, 5.41%
Essential Hypertension (primary hypertension): 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

Do you take Esidrix and have Gamma-glutamyltransferase increased?

- Check whether Gamma-glutamyltransferase increased is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Esidrix:

Esidrix (1,846 reports)

Browse all side effects of Esidrix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Gamma-glutamyltransferase increased:

Gamma-glutamyltransferase increased (1,345 drugs)

Browse all the conditions that are associated with Gamma-glutamyltransferase increased:

Gamma-glutamyltransferase increased (2,167 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide (the active ingredients of Esidrix) and Esidrix (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.