Esomeprazole sodium and Peripheral swelling - a phase IV clinical study of FDA data

Summary:

Peripheral swelling is reported as a side effect among people who take Esomeprazole sodium (esomeprazole sodium), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Xeljanz, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Peripheral swelling when taking Esomeprazole sodium. It is created by eHealthMe based on reports of 3,503 people who have side effects when taking Esomeprazole sodium from the FDA, and is updated regularly.

What is Esomeprazole sodium?

Esomeprazole sodium has active ingredients of esomeprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 3,583 Esomeprazole sodium users. Check the latest studies of Esomeprazole sodium.

What is Peripheral swelling?

Peripheral swelling is found to be associated with 2,182 drugs and 1,743 conditions by eHealthMe. Check the latest studies of Peripheral swelling.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

3,503 people reported to have side effects when taking Esomeprazole sodium.
Among them, 74 people (2.11%) have Peripheral swelling.

Could Esomeprazole sodium cause Peripheral swelling?

Among these 74 people:

How long have people been on Esomeprazole sodium when they have Peripheral swelling? *

What is the gender of people who have Peripheral swelling when taking Esomeprazole sodium? *

female: 85.71 %
male: 14.29 %

What is the age of people who have Peripheral swelling when taking Esomeprazole sodium? *

What are other drugs people take besides Esomeprazole sodium? *

What are other side effects people have besides Peripheral swelling? *

Joint Pain: 54 people, 72.97%
Nausea (feeling of having an urge to vomit): 53 people, 71.62%
Itching: 49 people, 66.22%
Pain: 47 people, 63.51%
Malaise (a feeling of general discomfort or uneasiness): 43 people, 58.11%
Dyspnea (difficult or laboured breathing): 41 people, 55.41%
Visual Impairment: 40 people, 54.05%
Rashes (redness): 40 people, 54.05%
Abdominal Pain: 39 people, 52.70%
Pain In Extremity: 37 people, 50.00%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 55 people, 74.32%
High Blood Pressure: 12 people, 16.22%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 11 people, 14.86%
Ill-Defined Disorder: 10 people, 13.51%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 10 people, 13.51%
Blood Pressure Abnormal: 9 people, 12.16%
Reflux Laryngitis (voice disorder caused by backflow of stomach fluids to the throat and voice box area): 9 people, 12.16%
Diabetes: 8 people, 10.81%
Adverse Drug Reaction: 7 people, 9.46%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 6 people, 8.11%

* Approximation only. Some reports may have incomplete information.

Do you take Esomeprazole sodium and have Peripheral swelling?

- Check whether Peripheral swelling is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Esomeprazole sodium:

Esomeprazole sodium (3,583 reports)

Browse all side effects of Esomeprazole sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Peripheral swelling:

Peripheral swelling (2,182 drugs)

Browse all the conditions that are associated with Peripheral swelling:

Peripheral swelling (1,743 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on esomeprazole sodium (the active ingredients of Esomeprazole sodium) and Esomeprazole sodium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.