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Ester c and Joint pain - a phase IV clinical study of FDA data

Summary:

Joint pain is reported as a side effect among people who take Ester c (l-ascorbic acid), especially for people who are female, 60+ old, also take Vitamin D3, and have Polycythaemia vera.

The phase IV clinical study analyzes which people have Joint pain when taking Ester c. It is created by eHealthMe based on reports of 284 people who have side effects when taking Ester c from the FDA, and is updated regularly.

What is Ester c?

Ester c has active ingredients of l-ascorbic acid. eHealthMe is studying from 306 Ester c users. Check the latest studies of Ester c.

What is Joint pain?

Joint pain is found to be associated with 3,330 drugs and 5,206 conditions by eHealthMe. Check the latest studies of Joint pain.

On Jul, 14, 2026

284 people reported to have side effects when taking Ester c.
Among them, 17 people (5.99%) have Joint pain.

Could Ester c cause Joint pain?

Among these 17 people:

What is the gender of people who have Joint pain when taking Ester c? *

  • female: 90.91 %
  • male: 9.09 %

What is the age of people who have Joint pain when taking Ester c? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 22.22 %
  • 50-59: 0.0 %
  • 60+: 77.78 %

What are other drugs people take besides Ester c? *

  1. Vitamin D3: 11 people, 64.71%
  2. Calcium: 9 people, 52.94%
  3. Clopidogrel: 6 people, 35.29%
  4. Jakafi: 6 people, 35.29%
  5. Biotin: 3 people, 17.65%
  6. Vitamin D: 3 people, 17.65%
  7. Miralax: 3 people, 17.65%
  8. Oxycodone: 3 people, 17.65%
  9. Ondansetron: 2 people, 11.76%
  10. Fish Oil: 2 people, 11.76%

What are other side effects people have besides Joint pain? *

  1. Back Pain: 10 people, 58.82%
  2. Weakness: 10 people, 58.82%
  3. Muscle Aches (muscle pain): 8 people, 47.06%
  4. Dizziness: 8 people, 47.06%
  5. Dyspnea (difficult or laboured breathing): 8 people, 47.06%
  6. Headache (pain in head): 8 people, 47.06%
  7. Fatigue (feeling of tiredness): 8 people, 47.06%
  8. Chills (felling of cold): 7 people, 41.18%
  9. Bone Pain: 7 people, 41.18%
  10. Stress And Anxiety: 7 people, 41.18%

What are the existing conditions these people have? *

  1. Primary Myelofibrosis (primary disorder of the bone marrow): 6 people, 35.29%
  2. Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 6 people, 35.29%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 11.76%
  4. Neuralgia (pain in one or more nerves): 2 people, 11.76%
  5. Vitamin D Decreased: 1 person, 5.88%
  6. High Blood Cholesterol: 1 person, 5.88%
  7. Blood Magnesium Decreased: 1 person, 5.88%
  8. Bowel Movement Irregularity: 1 person, 5.88%
  9. Cardiac Disorder: 1 person, 5.88%
  10. Constipation: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Ester c and have Joint pain?

- Check whether Joint pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ester c:

Joint pain treatments and more:

How severe was Joint pain and when was it recovered:

Expand to all the drugs that have ingredients of l-ascorbic acid:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ester c:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Joint pain:

Browse all the conditions that are associated with Joint pain:

How the study uses the data?

The study uses data from the FDA. It is based on l-ascorbic acid (the active ingredients of Ester c) and Ester c (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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