Estrace and Joint pain - a phase IV clinical study of FDA data

Summary:

We study 15,891 people who have side effects when taking Estrace. Joint pain is found, especially among people who are female, 60+ old, have been taking the drug for < 1 month, also take Synthroid and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people take Estrace and have Joint pain. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Oct, 03, 2023

15,891 people reported to have side effects when taking Estrace.
Among them, 664 people (4.18%) have Joint pain.


What is Estrace?

Estrace has active ingredients of estradiol. It is used in hormone replacement therapy. Currently, eHealthMe is studying from 16,298 Estrace users.

What is Joint pain?

Joint pain is found to be associated with 4,836 drugs and 4,988 conditions by eHealthMe. Currently, we are studying 506,133 people who have Joint pain.

Number of Estrace and Joint pain reports submitted per year:

Could Estrace cause Joint pain?

Time on Estrace when people have Joint pain *:

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Gender of people who have Joint pain when taking Estrace*:

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Age of people who have Joint pain when taking Estrace *:

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Common drugs people take besides Estrace *:

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Common side effects people have besides Joint pain *:

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Common conditions people have *:

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* Approximation only. Some reports may have incomplete information.

Do you take Estrace and have Joint pain?

Check whether Joint pain is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related studies

Estrace side effects by duration, gender and age:

Joint pain treatments and more:

Common drugs associated with Joint pain:

All the drugs that are associated with Joint pain:

Common conditions associated with Joint pain:

All the conditions that are associated with Joint pain:

How the study uses the data?

The study uses data from the FDA. It is based on estradiol (the active ingredients of Estrace) and Estrace (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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