Estrogel and Ear pain - a phase IV clinical study of FDA data
Summary:
Ear pain is reported as a side effect among people who take Estrogel (estradiol), especially for people who are female, 30-39 old, also take Celebrex, and have Ankylosing spondylitis.
The phase IV clinical study analyzes which people have Ear pain when taking Estrogel. It is created by eHealthMe based on reports of 2,659 people who have side effects when taking Estrogel from the FDA, and is updated regularly.
What is Estrogel?
Estrogel has active ingredients of estradiol. It is often used in menopause. eHealthMe is studying from 2,921 Estrogel users. Check the latest studies of Estrogel.
What is Ear pain?
Ear pain is found to be associated with 1,404 drugs and 1,884 conditions by eHealthMe. Check the latest studies of Ear pain.
2,659 people reported to have side effects when taking Estrogel.
Among them, 12 people (0.45%) have Ear pain.

Among these 12 people:
What is the gender of people who have Ear pain when taking Estrogel? *
- female: 71.43 %
- male: 28.57 %
What is the age of people who have Ear pain when taking Estrogel? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 50.0 %
- 40-49: 0.0 %
- 50-59: 16.67 %
- 60+: 33.33 %
What are other drugs people take besides Estrogel? *
- Methotrexate: 8 people, 66.67%
- Folic Acid: 8 people, 66.67%
- Escitalopram: 8 people, 66.67%
- Celebrex: 8 people, 66.67%
- Inflectra: 5 people, 41.67%
- Seroquel: 5 people, 41.67%
- Brexpiprazole: 5 people, 41.67%
- Quetiapine Fumarate: 3 people, 25.00%
- Calcium: 3 people, 25.00%
- Vitamin D3: 2 people, 16.67%
What are other side effects people have besides Ear pain? *
- Bacterial Infection: 10 people, 83.33%
- Otitis (ear infection): 9 people, 75.00%
- Malaise (a feeling of general discomfort or uneasiness): 9 people, 75.00%
- Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 8 people, 66.67%
- Pain: 4 people, 33.33%
- Fatigue (feeling of tiredness): 3 people, 25.00%
- Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 3 people, 25.00%
- Pain In Extremity: 3 people, 25.00%
- Sinusitis (inflammation of sinus): 3 people, 25.00%
- Dyspnea (difficult or laboured breathing): 3 people, 25.00%
What are the existing conditions these people have? *
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 8 people, 66.67%
- Ankylosing Spondylitis (type of arthritis affecting the spine): 8 people, 66.67%
- Immunodeficiency Common Variable: 2 people, 16.67%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 8.33%
- Osteoporosis (bones weak and more likely to break): 1 person, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Estrogel and have Ear pain?
- Check whether Ear pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Estrogel:
- Estrogel (2,921 reports)
Ear pain treatments and more:
- Ear pain (26,025 reports)
How severe was Ear pain and when was it recovered:
Expand to all the drugs that have ingredients of estradiol:
- Ear pain and drugs with ingredients of estradiol (175 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Estrogel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Ear pain:
- Ear pain (1,404 drugs)
Browse all the conditions that are associated with Ear pain:
- Ear pain (1,884 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on estradiol (the active ingredients of Estrogel) and Estrogel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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