Estrogenic substance and Joint pain - a phase IV clinical study of FDA data

Summary:

Joint pain is reported as a side effect among people who take Estrogenic substance (estrone), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Biaxin Xl, and have Lobar pneumonia.

The phase IV clinical study analyzes which people have Joint pain when taking Estrogenic substance. It is created by eHealthMe based on reports of 791 people who have side effects when taking Estrogenic substance from the FDA, and is updated regularly.

What is Estrogenic substance?

Estrogenic substance has active ingredients of estrone. It is often used in menopause. eHealthMe is studying from 867 Estrogenic substance users. Check the latest studies of Estrogenic substance.

What is Joint pain?

Joint pain is found to be associated with 3,328 drugs and 5,212 conditions by eHealthMe. Check the latest studies of Joint pain.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

791 people reported to have side effects when taking Estrogenic substance.
Among them, 26 people (3.29%) have Joint pain.

Could Estrogenic substance cause Joint pain?

Among these 26 people:

How long have people been on Estrogenic substance when they have Joint pain? *

What is the gender of people who have Joint pain when taking Estrogenic substance? *

female: 100 %
male: 0.0 %

What is the age of people who have Joint pain when taking Estrogenic substance? *

What are other drugs people take besides Estrogenic substance? *

What are other side effects people have besides Joint pain? *

Rashes (redness): 11 people, 42.31%
Joint Swelling: 10 people, 38.46%
Joint Stiffness: 8 people, 30.77%
Abasia (inability to walk): 7 people, 26.92%
Pain: 7 people, 26.92%
Pain In Extremity: 7 people, 26.92%
Weakness: 6 people, 23.08%
Muscle Aches (muscle pain): 6 people, 23.08%
Weight Bearing Difficulty (difficulty due to weight of thigh fat deposition): 6 people, 23.08%
Adverse Drug Reaction: 6 people, 23.08%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 15.38%
Lobar Pneumonia (a form of pneumonia that affects a large and continuous area of the lobe of a lung): 4 people, 15.38%
Pain: 3 people, 11.54%
High Blood Pressure: 3 people, 11.54%
Insomnia (sleeplessness): 2 people, 7.69%
Hypotension (abnormally low blood pressure): 2 people, 7.69%
Hormone Level Abnormal: 2 people, 7.69%
Sinusitis (inflammation of sinus): 2 people, 7.69%
Depression: 2 people, 7.69%
Pneumonia: 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Estrogenic substance and have Joint pain?

- Check whether Joint pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Estrogenic substance:

Estrogenic substance (867 reports)

Joint pain treatments and more:

Joint pain (542,936 reports)

Browse all side effects of Estrogenic substance:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Joint pain:

Joint pain (3,328 drugs)

Browse all the conditions that are associated with Joint pain:

Joint pain (5,212 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on estrone (the active ingredients of Estrogenic substance) and Estrogenic substance (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.