Estrogenic substance and Pain - a phase IV clinical study of FDA data

Summary:

Pain is reported as a side effect among people who take Estrogenic substance (estrone), especially for people who are female, 50-59 old, have been taking the drug for 2 - 5 years also take Lipitor, and have Lobar pneumonia.

The phase IV clinical study analyzes which people have Pain when taking Estrogenic substance. It is created by eHealthMe based on reports of 791 people who have side effects when taking Estrogenic substance from the FDA, and is updated regularly.

What is Estrogenic substance?

Estrogenic substance has active ingredients of estrone. It is often used in menopause. eHealthMe is studying from 867 Estrogenic substance users. Check the latest studies of Estrogenic substance.

What is Pain?

Pain is found to be associated with 3,807 drugs and 5,872 conditions by eHealthMe. Check the latest studies of Pain.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

791 people reported to have side effects when taking Estrogenic substance.
Among them, 47 people (5.94%) have Pain.

Could Estrogenic substance cause Pain?

Among these 47 people:

How long have people been on Estrogenic substance when they have Pain? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 100 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Pain when taking Estrogenic substance? *

  • female: 97.87 %
  • male: 2.13 %

What is the age of people who have Pain when taking Estrogenic substance? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 3.33 %
  • 30-39: 3.33 %
  • 40-49: 23.33 %
  • 50-59: 40.0 %
  • 60+: 30.0 %

What are other drugs people take besides Estrogenic substance? *

  1. Lipitor: 7 people, 14.89%
  2. Zoloft: 6 people, 12.77%
  3. Aspirin: 6 people, 12.77%
  4. Protonix: 6 people, 12.77%
  5. Biaxin Xl: 6 people, 12.77%
  6. Percocet: 6 people, 12.77%
  7. Trasylol: 5 people, 10.64%
  8. Lantus: 5 people, 10.64%
  9. Reglan: 5 people, 10.64%
  10. Xanax: 5 people, 10.64%

What are other side effects people have besides Pain? *

  1. Stress And Anxiety: 11 people, 23.40%
  2. Injury: 10 people, 21.28%
  3. Emotional Distress: 9 people, 19.15%
  4. High Blood Pressure: 8 people, 17.02%
  5. Joint Swelling: 8 people, 17.02%
  6. Fever: 7 people, 14.89%
  7. Depression: 7 people, 14.89%
  8. Joint Pain: 7 people, 14.89%
  9. Rashes (redness): 7 people, 14.89%
  10. Abasia (inability to walk): 6 people, 12.77%

What are the existing conditions these people have? *

  1. Lobar Pneumonia (a form of pneumonia that affects a large and continuous area of the lobe of a lung): 4 people, 8.51%
  2. Back Pain: 3 people, 6.38%
  3. Osteoporosis (bones weak and more likely to break): 2 people, 4.26%
  4. Pneumonia: 2 people, 4.26%
  5. Movement - Uncontrolled Or Slow: 2 people, 4.26%
  6. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 4.26%
  7. Muscle Spasms (muscle contraction): 2 people, 4.26%
  8. Neuralgia (pain in one or more nerves): 2 people, 4.26%
  9. Dry Skin: 2 people, 4.26%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 4.26%

* Approximation only. Some reports may have incomplete information.

Do you take Estrogenic substance and have Pain?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Estrogenic substance:

Pain treatments and more:

  • Pain (1,140,596 reports)

How severe was Pain and when was it recovered:

Expand to all the drugs that have ingredients of estrone:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Estrogenic substance:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pain:

  • Pain (3,807 drugs)

Browse all the conditions that are associated with Pain:

  • Pain (5,872 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on estrone (the active ingredients of Estrogenic substance) and Estrogenic substance (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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