Estropipate and Flushing aggravated - a phase IV clinical study of FDA data

Summary:

Flushing aggravated is reported as a side effect among people who take Estropipate (estropipate), especially for people who are female, 50-59 old, also take Synthroid, and have Asthma.

The phase IV clinical study analyzes which people have Flushing aggravated when taking Estropipate. It is created by eHealthMe based on reports of 1,633 people who have side effects when taking Estropipate from the FDA, and is updated regularly.

What is Estropipate?

Estropipate has active ingredients of estropipate. It is often used in hormone replacement therapy. eHealthMe is studying from 1,659 Estropipate users. Check the latest studies of Estropipate.

What is Flushing aggravated?

Flushing aggravated (the warm, red condition of human skin) is found to be associated with 1,455 drugs and 459 conditions by eHealthMe. Check the latest studies of Flushing aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

1,633 people reported to have side effects when taking Estropipate.
Among them, 15 people (0.92%) have Flushing aggravated.

Could Estropipate cause Flushing aggravated?

Among these 15 people:

What is the gender of people who have Flushing aggravated when taking Estropipate? *

female: 100 %
male: 0.0 %

What is the age of people who have Flushing aggravated when taking Estropipate? *

What are other drugs people take besides Estropipate? *

What are other side effects people have besides Flushing aggravated? *

Hypersensitivity: 9 people, 60.00%
Stress And Anxiety: 9 people, 60.00%
Sensation Of Foreign Body: 9 people, 60.00%
Dyspnea (difficult or laboured breathing): 9 people, 60.00%
Throat Tightness: 9 people, 60.00%
High Blood Pressure: 9 people, 60.00%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 9 people, 60.00%
Headache (pain in head): 9 people, 60.00%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 2 people, 13.33%
Generalised Erythema (redness of the skin all over the body): 1 person, 6.67%

What are the existing conditions these people have? *

Asthma: 9 people, 60.00%
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose): 8 people, 53.33%
Restless Leg Syndrome (a powerful urge to move your legs): 8 people, 53.33%
Postmenopause: 8 people, 53.33%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 8 people, 53.33%
High Blood Pressure: 8 people, 53.33%
Folate Deficiency (lack of folic acid): 8 people, 53.33%
Weakness: 7 people, 46.67%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 13.33%
Low Density Lipoprotein Increased (cholesterol increased in blood): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Estropipate and have Flushing aggravated?

- Check whether Flushing aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Estropipate:

Estropipate (1,659 reports)

Browse all side effects of Estropipate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Flushing aggravated:

Flushing aggravated (1,456 drugs)

Browse all the conditions that are associated with Flushing aggravated:

Flushing aggravated (459 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on estropipate (the active ingredients of Estropipate) and Estropipate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.