Estropipate and Nausea and vomiting - a phase IV clinical study of FDA data

Summary:

Nausea and vomiting is reported as a side effect among people who take Estropipate (estropipate), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Hydrochlorothiazide, and have Osteoporosis.

The phase IV clinical study analyzes which people have Nausea and vomiting when taking Estropipate. It is created by eHealthMe based on reports of 1,633 people who have side effects when taking Estropipate from the FDA, and is updated regularly.

What is Estropipate?

Estropipate has active ingredients of estropipate. It is often used in hormone replacement therapy. eHealthMe is studying from 1,659 Estropipate users. Check the latest studies of Estropipate.

What is Nausea and vomiting?

Nausea and vomiting is found to be associated with 3,712 drugs and 5,746 conditions by eHealthMe. Check the latest studies of Nausea and vomiting.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

1,633 people reported to have side effects when taking Estropipate.
Among them, 24 people (1.47%) have Nausea and vomiting.

Could Estropipate cause Nausea and vomiting?

Among these 24 people:

How long have people been on Estropipate when they have Nausea and vomiting? *

What is the gender of people who have Nausea and vomiting when taking Estropipate? *

female: 91.67 %
male: 8.33 %

What is the age of people who have Nausea and vomiting when taking Estropipate? *

What are other drugs people take besides Estropipate? *

Hydrochlorothiazide: 5 people, 20.83%
Medroxyprogesterone Acetate: 4 people, 16.67%
Lisinopril: 4 people, 16.67%
Plaquenil: 3 people, 12.50%
Premarin: 3 people, 12.50%
Magnesium: 2 people, 8.33%
Protonix: 2 people, 8.33%
Clopidogrel Bisulfate: 2 people, 8.33%
Norfloxacin: 2 people, 8.33%
Crestor: 2 people, 8.33%

What are other side effects people have besides Nausea and vomiting? *

Nausea (feeling of having an urge to vomit): 11 people, 45.83%
Fatigue (feeling of tiredness): 8 people, 33.33%
Hypotension (abnormally low blood pressure): 7 people, 29.17%
Diarrhea: 6 people, 25.00%
Dehydration (dryness resulting from the removal of water): 6 people, 25.00%
Fever: 5 people, 20.83%
Drug Ineffective: 4 people, 16.67%
Abdominal Pain Upper: 4 people, 16.67%
Rashes (redness): 4 people, 16.67%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 3 people, 12.50%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 4 people, 16.67%
Urinary Tract Infection: 2 people, 8.33%
Arrhythmia Supraventricular (irregular heartbeat supraventricular origin): 2 people, 8.33%
Heart Rate Increased: 2 people, 8.33%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 2 people, 8.33%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 8.33%
Nephrotic Syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema): 2 people, 8.33%
Acute Kidney Failure: 2 people, 8.33%
Pain: 2 people, 8.33%
Personality Disorder: 1 person, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Estropipate and have Nausea and vomiting?

- Check whether Nausea and vomiting is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Estropipate:

Estropipate (1,659 reports)

Browse all side effects of Estropipate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nausea and vomiting:

Nausea and vomiting (3,712 drugs)

Browse all the conditions that are associated with Nausea and vomiting:

Nausea and vomiting (5,746 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on estropipate (the active ingredients of Estropipate) and Estropipate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.