Eszopiclone and Poor quality sleep - a phase IV clinical study of FDA data

Summary:

Poor quality sleep is reported as a side effect among people who take Eszopiclone (eszopiclone), especially for people who are female, 20-29 old, have been taking the drug for 1 - 6 months also take Vitamin D3, and have Hallucinations.

The phase IV clinical study analyzes which people have Poor quality sleep when taking Eszopiclone. It is created by eHealthMe based on reports of 4,164 people who have side effects when taking Eszopiclone from the FDA, and is updated regularly.

What is Eszopiclone?

Eszopiclone has active ingredients of eszopiclone. It is often used in insomnia. eHealthMe is studying from 4,259 Eszopiclone users. Check the latest studies of Eszopiclone.

What is Poor quality sleep?

Poor quality sleep is found to be associated with 1,255 drugs and 1,167 conditions by eHealthMe. Check the latest studies of Poor quality sleep.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

4,164 people reported to have side effects when taking Eszopiclone.
Among them, 21 people (0.5%) have Poor quality sleep.

Could Eszopiclone cause Poor quality sleep?

Among these 21 people:

How long have people been on Eszopiclone when they have Poor quality sleep? *

What is the gender of people who have Poor quality sleep when taking Eszopiclone? *

female: 61.9 %
male: 38.1 %

What is the age of people who have Poor quality sleep when taking Eszopiclone? *

What are other drugs people take besides Eszopiclone? *

Zopiclone: 5 people, 23.81%
Ranitidine: 5 people, 23.81%
Acyclovir: 5 people, 23.81%
Celecoxib: 5 people, 23.81%
Lunesta: 5 people, 23.81%
Olanzapine: 5 people, 23.81%
Acetaminophen: 5 people, 23.81%
Vitamin D3: 5 people, 23.81%
Cetirizine Hydrochloride: 4 people, 19.05%
Tylenol: 3 people, 14.29%

What are other side effects people have besides Poor quality sleep? *

Nausea (feeling of having an urge to vomit): 11 people, 52.38%
Stress And Anxiety: 11 people, 52.38%
Drug Ineffective: 8 people, 38.10%
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur): 8 people, 38.10%
Feeling Abnormal: 7 people, 33.33%
Fatigue (feeling of tiredness): 7 people, 33.33%
Cough: 7 people, 33.33%
Headache (pain in head): 7 people, 33.33%
Depression: 6 people, 28.57%
Sleep Walking (walking during sleep): 6 people, 28.57%

What are the existing conditions these people have? *

Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 5 people, 23.81%
Hallucinations (sensations that appear real but are created by your mind): 5 people, 23.81%
Rapid Eye Movements Sleep Abnormal: 3 people, 14.29%
Affective Disorder (mental disorder): 3 people, 14.29%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1 person, 4.76%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 4.76%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Eszopiclone and have Poor quality sleep?

- Check whether Poor quality sleep is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Eszopiclone:

Eszopiclone (4,259 reports)

Browse all side effects of Eszopiclone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Poor quality sleep:

Poor quality sleep (1,255 drugs)

Browse all the conditions that are associated with Poor quality sleep:

Poor quality sleep (1,167 conditions)

Related publications that referenced our studies

Lai SW, Lai HC, Lin CL, Liao KF, "Zopiclone use associated with increased risk of acute pancreatitis: a case–control study in Taiwan", International journal of clinical practice, 2015 Nov .
Lai SW, Lai HC, Lin CL, Liao KF, "Zopiclone use associated with increased risk of acute pancreatitis: a case–control study in Taiwan", International journal of clinical practice, 2015 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on eszopiclone (the active ingredients of Eszopiclone) and Eszopiclone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.