Etoposide and Axonal neuropathy - a phase IV clinical study of FDA data

Summary:

Axonal neuropathy is reported as a side effect among people who take Etoposide (etoposide), especially for people who are female, 2-9 old, have been taking the drug for < 1 month also take Methotrexate, and have Histiocytosis haematophagic.

The phase IV clinical study analyzes which people have Axonal neuropathy when taking Etoposide. It is created by eHealthMe based on reports of 77,756 people who have side effects when taking Etoposide from the FDA, and is updated regularly.

What is Etoposide?

Etoposide has active ingredients of etoposide. eHealthMe is studying from 77,815 Etoposide users. Check the latest studies of Etoposide.

What is Axonal neuropathy?

Axonal neuropathy (dysfunction of axon nerves) is found to be associated with 120 drugs and 383 conditions by eHealthMe. Check the latest studies of Axonal neuropathy.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

77,756 people reported to have side effects when taking Etoposide.
Among them, 17 people (0.02%) have Axonal neuropathy.

Could Etoposide cause Axonal neuropathy?

Among these 17 people:

How long have people been on Etoposide when they have Axonal neuropathy? *

What is the gender of people who have Axonal neuropathy when taking Etoposide? *

female: 76.47 %
male: 23.53 %

What is the age of people who have Axonal neuropathy when taking Etoposide? *

What are other drugs people take besides Etoposide? *

What are other side effects people have besides Axonal neuropathy? *

Myelopathy (any neurologic deficit related to the spinal cord): 3 people, 17.65%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 3 people, 17.65%
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 3 people, 17.65%
Histiocytosis Haematophagic: 2 people, 11.76%
Quadriplegia (a four limb paralysis): 2 people, 11.76%
Joint Pain: 2 people, 11.76%
Areflexia (absence of a reflex): 2 people, 11.76%
Hepatic Function Abnormal: 2 people, 11.76%
Fever: 2 people, 11.76%
Encephalopathy (functioning of the brain is affected by some agent or condition): 2 people, 11.76%

What are the existing conditions these people have? *

Histiocytosis Haematophagic: 8 people, 47.06%
Febrile Bone Marrow Aplasia (bone marrow greatly decreases or stops production of blood cells): 3 people, 17.65%
Burkitt's Lymphoma Stage Iv (blood cancer stage iv): 3 people, 17.65%
Bacterial Pyelonephritis (bacterial kidney infection): 3 people, 17.65%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 1 person, 5.88%
Neoplasm Recurrence (reoccurrence of tumour): 1 person, 5.88%
Neoplasm Progression (growth of tumour): 1 person, 5.88%
Metastasis (spreadable cancer to other organ from origin): 1 person, 5.88%
Lung Cancer - Small Cell (lung cancer): 1 person, 5.88%
Lambert-Eaton Syndrome (this means your immune system mistakenly targets healthy cells and tissues in the body): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Etoposide and have Axonal neuropathy?

- Check whether Axonal neuropathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Etoposide:

Etoposide (77,815 reports)

Browse all side effects of Etoposide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Axonal neuropathy:

Axonal neuropathy (120 drugs)

Browse all the conditions that are associated with Axonal neuropathy:

Axonal neuropathy (383 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on etoposide (the active ingredients of Etoposide) and Etoposide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.