Etoposide and Mediastinal mass - a phase IV clinical study of FDA data

Summary:

Mediastinal mass is reported as a side effect among people who take Etoposide (etoposide), especially for people who are male, 20-29 old, have been taking the drug for < 1 month also take Cyclophosphamide, and have Non-hodgkin's lymphoma.

The phase IV clinical study analyzes which people have Mediastinal mass when taking Etoposide. It is created by eHealthMe based on reports of 77,756 people who have side effects when taking Etoposide from the FDA, and is updated regularly.

What is Etoposide?

Etoposide has active ingredients of etoposide. eHealthMe is studying from 77,815 Etoposide users. Check the latest studies of Etoposide.

What is Mediastinal mass?

Mediastinal mass (mass in the part of the chest that separates the lungs) is found to be associated with 109 drugs and 170 conditions by eHealthMe. Check the latest studies of Mediastinal mass.

On Jul, 26, 2026

77,756 people reported to have side effects when taking Etoposide.
Among them, 21 people (0.03%) have Mediastinal mass.

Among these 21 people:

How long have people been on Etoposide when they have Mediastinal mass? *

What is the gender of people who have Mediastinal mass when taking Etoposide? *

female: 36.84 %
male: 63.16 %

What is the age of people who have Mediastinal mass when taking Etoposide? *

What are other drugs people take besides Etoposide? *

Cyclophosphamide: 6 people, 28.57%
Cisplatin: 5 people, 23.81%
Prednisolone: 3 people, 14.29%
Doxorubicin Hydrochloride: 3 people, 14.29%
Lenalidomide: 3 people, 14.29%
Methotrexate: 2 people, 9.52%
Carmustine: 1 person, 4.76%
Busulfex: 1 person, 4.76%
Clofarabine: 1 person, 4.76%
Bortezomib: 1 person, 4.76%

What are other side effects people have besides Mediastinal mass? *

Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 6 people, 28.57%
Disease Progression: 5 people, 23.81%
Febrile Neutropenia (fever with reduced white blood cells): 5 people, 23.81%
Disease Recurrence: 4 people, 19.05%
Pleural Effusion (water on the lungs): 4 people, 19.05%
Dyspnea (difficult or laboured breathing): 4 people, 19.05%
Malignant Neoplasm Progression (cancer tumour came back): 3 people, 14.29%
Small Intestinal Obstruction (blockage in small intestine): 3 people, 14.29%
Plasmablastic Lymphoma (aggressive b-cell cancer occurring mainly in the jaws and oral cavity): 3 people, 14.29%
Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 3 people, 14.29%

What are the existing conditions these people have? *

Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 4 people, 19.05%
Testis Cancer (testes cancer): 3 people, 14.29%
Plasmablastic Lymphoma (aggressive b-cell cancer occurring mainly in the jaws and oral cavity): 3 people, 14.29%
T-Cell Lymphoma (a blood cell cancer): 1 person, 4.76%
Leukaemia (blood or bone marrow cancer): 1 person, 4.76%
Inflammatory Bowel Disease: 1 person, 4.76%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Etoposide and have Mediastinal mass?

- Check whether Mediastinal mass is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Etoposide:

Etoposide (77,815 reports)

Browse all side effects of Etoposide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Mediastinal mass:

Mediastinal mass (109 drugs)

Browse all the conditions that are associated with Mediastinal mass:

Mediastinal mass (170 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on etoposide (the active ingredients of Etoposide) and Etoposide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.