Evening primrose and Ear buzzing - a phase IV clinical study of FDA data

Summary:

Ear buzzing is reported as a side effect among people who take Evening primrose (evening primrose oil), especially for people who are female, 60+ old, also take Magnesium, and have Migraine.

The phase IV clinical study analyzes which people have Ear buzzing when taking Evening primrose. It is created by eHealthMe based on reports of 1,534 people who have side effects when taking Evening primrose from the FDA, and is updated regularly.

What is Evening primrose?

Evening primrose has active ingredients of evening primrose oil. It is often used in breast pain. eHealthMe is studying from 1,794 Evening primrose users. Check the latest studies of Evening primrose.

What is Ear buzzing?

Ear buzzing is found to be associated with 2,099 drugs and 3,108 conditions by eHealthMe. Check the latest studies of Ear buzzing.

On Jul, 03, 2026

1,534 people reported to have side effects when taking Evening primrose.
Among them, 18 people (1.17%) have Ear buzzing.

Could Evening primrose cause Ear buzzing?

Among these 18 people:

What is the gender of people who have Ear buzzing when taking Evening primrose? *

female: 94.12 %
male: 5.88 %

What is the age of people who have Ear buzzing when taking Evening primrose? *

What are other drugs people take besides Evening primrose? *

What are other side effects people have besides Ear buzzing? *

Joint Pain: 7 people, 38.89%
Weakness: 5 people, 27.78%
Rashes (redness): 5 people, 27.78%
Balance Disorder: 5 people, 27.78%
Dizziness: 5 people, 27.78%
Suicidal Ideation: 5 people, 27.78%
Memory Loss: 5 people, 27.78%
Abdominal Pain Upper: 4 people, 22.22%
Fatigue (feeling of tiredness): 4 people, 22.22%
Gait Disturbance: 4 people, 22.22%

What are the existing conditions these people have? *

Polymyalgia Rheumatica (pain in many muscles): 3 people, 16.67%
Migraine (headache): 3 people, 16.67%
Urinary Tract Infection: 1 person, 5.56%
Temporal Arteritis (inflammation and damage to blood vessels that supply the head area): 1 person, 5.56%
Stress And Anxiety: 1 person, 5.56%
Sinusitis (inflammation of sinus): 1 person, 5.56%
Osteoporosis (bones weak and more likely to break): 1 person, 5.56%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 5.56%
Insomnia (sleeplessness): 1 person, 5.56%
Hypersensitivity: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Evening primrose and have Ear buzzing?

- Check whether Ear buzzing is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Evening primrose:

Evening primrose (1,794 reports)

Ear buzzing treatments and more:

Ear buzzing (58,552 reports)

Browse all side effects of Evening primrose:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ear buzzing:

Ear buzzing (2,099 drugs)

Browse all the conditions that are associated with Ear buzzing:

Ear buzzing (3,108 conditions)

Related publications that referenced our studies

Min IS, Lee JY, Jung TS, Kang NK, Park BB, Kim BK, "Development of a Complete Atrioventricular Block Associated with Intake of Evening Primrose Oil", The Korean Journal of Medicine, 2016 May .
Min IS, Lee JY, Jung TS, Kang NK, Park BB, Kim BK, "Development of a Complete Atrioventricular Block Associated with Intake of Evening Primrose Oil", The Korean Journal of Medicine, 2016 May .

How the study uses the data?

The study uses data from the FDA. It is based on evening primrose oil (the active ingredients of Evening primrose) and Evening primrose (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.