Evening primrose and Itching - a phase IV clinical study of FDA data

Summary:

Itching is reported as a side effect among people who take Evening primrose (evening primrose oil), especially for people who are female, 60+ old, also take Vitamin C, and have High blood cholesterol.

The phase IV clinical study analyzes which people have Itching when taking Evening primrose. It is created by eHealthMe based on reports of 1,534 people who have side effects when taking Evening primrose from the FDA, and is updated regularly.

What is Evening primrose?

Evening primrose has active ingredients of evening primrose oil. It is often used in breast pain. eHealthMe is studying from 1,794 Evening primrose users. Check the latest studies of Evening primrose.

What is Itching?

Itching is found to be associated with 3,210 drugs and 4,533 conditions by eHealthMe. Check the latest studies of Itching.

On Jul, 15, 2026

1,534 people reported to have side effects when taking Evening primrose.
Among them, 73 people (4.76%) have Itching.

Among these 73 people:

What is the gender of people who have Itching when taking Evening primrose? *

female: 90 %
male: 10 %

What is the age of people who have Itching when taking Evening primrose? *

What are other drugs people take besides Evening primrose? *

What are other side effects people have besides Itching? *

Rashes (redness): 22 people, 30.14%
Malaise (a feeling of general discomfort or uneasiness): 13 people, 17.81%
Diarrhea: 10 people, 13.70%
Dizziness: 10 people, 13.70%
Skin Blushing/flushing (a sudden reddening of the face, neck): 9 people, 12.33%
Hot Flush (sudden feelings of heat): 8 people, 10.96%
Fatigue (feeling of tiredness): 8 people, 10.96%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 8 people, 10.96%
Urticaria (rash of round, red welts on the skin that itch intensely): 8 people, 10.96%
Urinary Tract Infection: 8 people, 10.96%

What are the existing conditions these people have? *

High Blood Cholesterol: 9 people, 12.33%
Multiple Myeloma (cancer of the plasma cells): 7 people, 9.59%
High Blood Pressure: 6 people, 8.22%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 6.85%
Joint Pain: 4 people, 5.48%
Osteopenia (a condition where bone mineral density is lower than normal): 4 people, 5.48%
Osteoporosis (bones weak and more likely to break): 3 people, 4.11%
Immunodeficiency Common Variable: 3 people, 4.11%
Urinary Tract Infection: 3 people, 4.11%
Cardiac Disorder: 3 people, 4.11%

* Approximation only. Some reports may have incomplete information.

Do you take Evening primrose and have Itching?

- Check whether Itching is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Evening primrose:

Evening primrose (1,794 reports)

Itching treatments and more:

Itching (398,821 reports)

Browse all side effects of Evening primrose:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Itching:

Itching (3,210 drugs)

Browse all the conditions that are associated with Itching:

Itching (4,533 conditions)

Related publications that referenced our studies

Min IS, Lee JY, Jung TS, Kang NK, Park BB, Kim BK, "Development of a Complete Atrioventricular Block Associated with Intake of Evening Primrose Oil", The Korean Journal of Medicine, 2016 May .
Min IS, Lee JY, Jung TS, Kang NK, Park BB, Kim BK, "Development of a Complete Atrioventricular Block Associated with Intake of Evening Primrose Oil", The Korean Journal of Medicine, 2016 May .

How the study uses the data?

The study uses data from the FDA. It is based on evening primrose oil (the active ingredients of Evening primrose) and Evening primrose (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.