Evista and Herniated nucleus pulposus (slipped disk) - a phase IV clinical study of FDA data

Summary:

Herniated nucleus pulposus (slipped disk) is reported as a side effect among people who take Evista (raloxifene hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years also take Fosamax, and have Breast cancer.

The phase IV clinical study analyzes which people have Herniated nucleus pulposus (slipped disk) when taking Evista. It is created by eHealthMe based on reports of 25,442 people who have side effects when taking Evista from the FDA, and is updated regularly.

What is Evista?

Evista has active ingredients of raloxifene hydrochloride. It is often used in osteoporosis. eHealthMe is studying from 25,891 Evista users. Check the latest studies of Evista.

What is Herniated nucleus pulposus (slipped disk)?

Herniated nucleus pulposus (slipped disk) is found to be associated with 583 drugs and 909 conditions by eHealthMe. Check the latest studies of Herniated nucleus pulposus (slipped disk).



On Jul, 05, 2026

25,442 people reported to have side effects when taking Evista.
Among them, 43 people (0.17%) have Herniated nucleus pulposus (slipped disk).

Could Evista cause Herniated nucleus pulposus (slipped disk)?

Among these 43 people:

How long have people been on Evista when they have Herniated nucleus pulposus (slipped disk)? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 50 %
  • 5 - 10 years: 50 %
  • 10+ years: 0.0 %

What is the gender of people who have Herniated nucleus pulposus (slipped disk) when taking Evista? *

  • female: 97.5 %
  • male: 2.5 %

What is the age of people who have Herniated nucleus pulposus (slipped disk) when taking Evista? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 2.86 %
  • 50-59: 62.86 %
  • 60+: 34.29 %

What are other drugs people take besides Evista? *

  1. Fosamax: 38 people, 88.37%
  2. Ambien: 27 people, 62.79%
  3. Celebrex: 27 people, 62.79%
  4. Nexium: 27 people, 62.79%
  5. Zometa: 27 people, 62.79%
  6. Neurontin: 26 people, 60.47%
  7. Zoloft: 26 people, 60.47%
  8. Lyrica: 26 people, 60.47%
  9. Zocor: 24 people, 55.81%
  10. Lexapro: 24 people, 55.81%

What are other side effects people have besides Herniated nucleus pulposus (slipped disk)? *

  1. Pain In Extremity: 34 people, 79.07%
  2. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 33 people, 76.74%
  3. Stress And Anxiety: 32 people, 74.42%
  4. Joint Pain: 31 people, 72.09%
  5. Memory Loss: 30 people, 69.77%
  6. Urinary Tract Infection: 29 people, 67.44%
  7. Pain: 29 people, 67.44%
  8. Hypoaesthesia (reduced sense of touch or sensation): 28 people, 65.12%
  9. Emotional Distress: 28 people, 65.12%
  10. Injury: 27 people, 62.79%

What are the existing conditions these people have? *

  1. Hypercalcaemia (elevated calcium (ca+) level in the blood): 21 people, 48.84%
  2. Breast Cancer: 21 people, 48.84%
  3. Breast Cancer Metastatic: 20 people, 46.51%
  4. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 6.98%
  5. Asthma: 3 people, 6.98%
  6. Allergic Rhinitis: 3 people, 6.98%
  7. Pain: 2 people, 4.65%
  8. Hormone Level Abnormal: 2 people, 4.65%
  9. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 2.33%
  10. Psoriasis (immune-mediated disease that affects the skin): 1 person, 2.33%

* Approximation only. Some reports may have incomplete information.

Do you take Evista and have Herniated nucleus pulposus (slipped disk)?

- Check whether Herniated nucleus pulposus (slipped disk) is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Evista:

Herniated nucleus pulposus (slipped disk) treatments and more:

How severe was Herniated nucleus pulposus (slipped disk) and when was it recovered:

Expand to all the drugs that have ingredients of raloxifene hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Evista:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Herniated nucleus pulposus (slipped disk):

Browse all the conditions that are associated with Herniated nucleus pulposus (slipped disk):


How the study uses the data?

The study uses data from the FDA. It is based on raloxifene hydrochloride (the active ingredients of Evista) and Evista (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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