Evomela and Fever - a phase IV clinical study of FDA data

Summary:

Fever is reported as a side effect among people who take Evomela (melphalan hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Sodium Chloride, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Fever when taking Evomela. It is created by eHealthMe based on reports of 104 people who have side effects when taking Evomela from the FDA, and is updated regularly.

What is Evomela?

Evomela has active ingredients of melphalan hydrochloride. eHealthMe is studying from 104 Evomela users. Check the latest studies of Evomela.

What is Fever?

Fever is found to be associated with 3,495 drugs and 6,196 conditions by eHealthMe. Check the latest studies of Fever.

On Jul, 18, 2026

104 people reported to have side effects when taking Evomela.
Among them, 25 people (24.04%) have Fever.

Among these 25 people:

How long have people been on Evomela when they have Fever? *

What is the gender of people who have Fever when taking Evomela? *

female: 58.82 %
male: 41.18 %

What is the age of people who have Fever when taking Evomela? *

What are other drugs people take besides Evomela? *

What are other side effects people have besides Fever? *

Diarrhea: 15 people, 60.00%
Thrombocytopenia (decrease of platelets in blood): 12 people, 48.00%
Nausea (feeling of having an urge to vomit): 12 people, 48.00%
Anaemia (lack of blood): 11 people, 44.00%
Hypokalemia (low potassium): 9 people, 36.00%
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 7 people, 28.00%
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low): 7 people, 28.00%
Abdominal Pain: 7 people, 28.00%
Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 7 people, 28.00%
Constipation: 6 people, 24.00%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 7 people, 28.00%
Primary Amyloidosis (disease that occurs when substances called amyloid proteins build up in your organs): 5 people, 20.00%
Bone Marrow Conditioning Regimen: 4 people, 16.00%
Osteoporosis (bones weak and more likely to break): 3 people, 12.00%
Nausea (feeling of having an urge to vomit): 3 people, 12.00%
High Blood Pressure: 2 people, 8.00%
Nausea And Vomiting: 2 people, 8.00%
Urination - Excessive Volume: 2 people, 8.00%
Constipation: 2 people, 8.00%
Poems Syndrome (blood disorder that affects many parts of the body and causes many symptoms): 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

Do you take Evomela and have Fever?

- Check whether Fever is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Evomela:

Evomela (104 reports)

Fever treatments and more:

Fever (498,666 reports)

Browse all side effects of Evomela:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fever:

Fever (3,495 drugs)

Browse all the conditions that are associated with Fever:

Fever (6,196 conditions)

Related publications that referenced our studies

Schiller D, Maieron A, Sch?fl R, Donnerer J, "Drug fever due to a single dose of pantoprazole", Pharmacology, 2015 Jan .
Schiller D, Maieron A, Sch?fl R, Donnerer J, "Drug fever due to a single dose of pantoprazole", Pharmacology, 2015 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on melphalan hydrochloride (the active ingredients of Evomela) and Evomela (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.