Evoxac and Acquired oesophageal web - a phase IV clinical study of FDA data

Summary:

Acquired oesophageal web is reported as a side effect among people who take Evoxac (cevimeline hydrochloride), especially for people who are female, 50-59 old, also take Levaquin, and have Breast cancer.

The phase IV clinical study analyzes which people have Acquired oesophageal web when taking Evoxac. It is created by eHealthMe based on reports of 1,960 people who have side effects when taking Evoxac from the FDA, and is updated regularly.

What is Evoxac?

Evoxac has active ingredients of cevimeline hydrochloride. It is often used in sjogren syndrome. eHealthMe is studying from 2,028 Evoxac users. Check the latest studies of Evoxac.

What is Acquired oesophageal web?

Acquired oesophageal web (structural abnormalities in the oesophagus) is found to be associated with 285 drugs and 230 conditions by eHealthMe. Check the latest studies of Acquired oesophageal web.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

1,960 people reported to have side effects when taking Evoxac.
Among them, 14 people (0.71%) have Acquired oesophageal web.

Could Evoxac cause Acquired oesophageal web?

Among these 14 people:

What is the gender of people who have Acquired oesophageal web when taking Evoxac? *

female: 100 %
male: 0.0 %

What is the age of people who have Acquired oesophageal web when taking Evoxac? *

What are other drugs people take besides Evoxac? *

What are other side effects people have besides Acquired oesophageal web? *

Urinary Tract Infection: 14 people, 100.00%
Injury: 14 people, 100.00%
Flatulence (flatus expelled through the anus): 14 people, 100.00%
Foot Deformity (functional disability of foot): 14 people, 100.00%
Gastrointestinal Inflammation (inflammation of stomach and intestine): 14 people, 100.00%
Genital Herpes (herpes infection of genital): 14 people, 100.00%
Glossitis (infection of tongue with soreness): 14 people, 100.00%
Groin Pain: 14 people, 100.00%
Haemolytic Anaemia (anaemia due to haemolysis): 14 people, 100.00%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 14 people, 100.00%

What are the existing conditions these people have? *

Breast Cancer: 8 people, 57.14%
Osteoporosis (bones weak and more likely to break): 4 people, 28.57%
Multiple Myeloma (cancer of the plasma cells): 4 people, 28.57%
Metastases To Bone (cancer spreads to bone): 4 people, 28.57%
Sleep Disorder: 1 person, 7.14%
Nervousness: 1 person, 7.14%
Nervous System Disorder (a general class of medical conditions affecting the nervous system): 1 person, 7.14%
High Blood Pressure: 1 person, 7.14%
Arrhythmias (irregular heartbeat): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Evoxac and have Acquired oesophageal web?

- Check whether Acquired oesophageal web is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Evoxac:

Evoxac (2,028 reports)

Browse all side effects of Evoxac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Acquired oesophageal web:

Acquired oesophageal web (285 drugs)

Browse all the conditions that are associated with Acquired oesophageal web:

Acquired oesophageal web (230 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cevimeline hydrochloride (the active ingredients of Evoxac) and Evoxac (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.