Evoxac and Hot flush - a phase IV clinical study of FDA data

Summary:

Hot flush is reported as a side effect among people who take Evoxac (cevimeline hydrochloride), especially for people who are 50-59 old, have been taking the drug for 5 - 10 years also take Cymbalta, and have Fibromyalgia.

The phase IV clinical study analyzes which people have Hot flush when taking Evoxac. It is created by eHealthMe based on reports of 1,960 people who have side effects when taking Evoxac from the FDA, and is updated regularly.

What is Evoxac?

Evoxac has active ingredients of cevimeline hydrochloride. It is often used in sjogren syndrome. eHealthMe is studying from 2,028 Evoxac users. Check the latest studies of Evoxac.

What is Hot flush?

Hot flush (sudden feelings of heat) is found to be associated with 1,772 drugs and 2,348 conditions by eHealthMe. Check the latest studies of Hot flush.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

1,960 people reported to have side effects when taking Evoxac.
Among them, 12 people (0.61%) have Hot flush.

Among these 12 people:

How long have people been on Evoxac when they have Hot flush? *

What is the age of people who have Hot flush when taking Evoxac? *

What are other drugs people take besides Evoxac? *

What are other side effects people have besides Hot flush? *

Joint Pain: 9 people, 75.00%
Dyspnea (difficult or laboured breathing): 8 people, 66.67%
Weight Increased: 8 people, 66.67%
Withdrawal Syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance): 7 people, 58.33%
Feeling Cold: 7 people, 58.33%
Dizziness: 5 people, 41.67%
Drug Ineffective: 5 people, 41.67%
Hyperhidrosis (abnormally increased sweating): 5 people, 41.67%
Nasopharyngitis (inflammation of the nasopharynx): 4 people, 33.33%
Bacterial Infection: 4 people, 33.33%

What are the existing conditions these people have? *

Fibromyalgia (a long-term condition which causes pain all over the body): 7 people, 58.33%
Chronic Fatigue Syndrome (disorder that causes extreme fatigue): 4 people, 33.33%
Neuropathy Peripheral (surface nerve damage): 3 people, 25.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 16.67%
Stress And Anxiety: 1 person, 8.33%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 8.33%
Menopause (end of monthly cycles in women): 1 person, 8.33%
Indigestion: 1 person, 8.33%
Hypersensitivity: 1 person, 8.33%
Dry Eyes (lack of adequate tears): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Evoxac and have Hot flush?

- Check whether Hot flush is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Evoxac:

Evoxac (2,028 reports)

Hot flush treatments and more:

Hot flush (91,208 reports)

Browse all side effects of Evoxac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hot flush:

Hot flush (1,772 drugs)

Browse all the conditions that are associated with Hot flush:

Hot flush (2,348 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cevimeline hydrochloride (the active ingredients of Evoxac) and Evoxac (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.