Evrysdi and Death - a phase IV clinical study of FDA data

Summary:

Death is reported as a side effect among people who take Evrysdi (risdiplam), especially for people who are male, 0-1 old, have been taking the drug for 1 - 2 years also take Spinraza, and have Spinal muscular atrophy.

The study is created by eHealthMe based on reports of 2,321 people who have side effects when taking Evrysdi from the FDA, and is updated regularly.

What is Evrysdi?

Evrysdi has active ingredients of risdiplam. eHealthMe is studying from 2,323 Evrysdi users. Check the latest studies of Evrysdi.

On Jul, 13, 2026

2,321 people reported to have side effects when taking Evrysdi.
Among them, 99 people (4.27%) died.

Among these 99 people:

How long have people been on Evrysdi when they died? *

What is the gender of people who died when taking Evrysdi? *

female: 38.75 %
male: 61.25 %

What is the age of people who died when taking Evrysdi? *

What are other drugs people take besides Evrysdi? *

What are other side effects people have before they died? *

Pneumonia: 7 people, 7.07%
Dyspnea (difficult or laboured breathing): 3 people, 3.03%
Fever: 3 people, 3.03%
Viral Infection: 2 people, 2.02%
The Flu (the flu is caused by an influenza virus): 2 people, 2.02%
Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 1 person, 1.01%
Hypersensitivity: 1 person, 1.01%
Hyperhidrosis (abnormally increased sweating): 1 person, 1.01%
Heart Rate Increased: 1 person, 1.01%
Heart Rate Decreased: 1 person, 1.01%

What are the existing conditions these people have? *

Spinal Muscular Atrophy (wasting of spinal muscles): 86 people, 86.87%
Osteopenia (a condition where bone mineral density is lower than normal): 1 person, 1.01%
Neuromyopathy (disease of both muscles and nerves): 1 person, 1.01%
Constipation: 1 person, 1.01%
Asthma: 1 person, 1.01%

* Approximation only. Some reports may have incomplete information.

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Evrysdi:

Evrysdi (2,323 reports)

Expand to all the drugs that have ingredients of risdiplam:

Death and drugs with ingredients of risdiplam

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Evrysdi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Death:

Death (3,126 drugs)

Browse all the conditions that are associated with Death:

Death (3,686 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on risdiplam (the active ingredients of Evrysdi) and Evrysdi (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.