Excedrin and Malabsorption - a phase IV clinical study of FDA data

Summary:

Malabsorption is reported as a side effect among people who take Excedrin (acetaminophen; aspirin; caffeine), especially for people who are female, 60+ old, also take Benicar Hct, and have High blood pressure.

The phase IV clinical study analyzes which people have Malabsorption when taking Excedrin. It is created by eHealthMe based on reports of 21,620 people who have side effects when taking Excedrin from the FDA, and is updated regularly.

What is Excedrin?

Excedrin has active ingredients of acetaminophen; aspirin; caffeine. It is often used in headache. eHealthMe is studying from 22,740 Excedrin users. Check the latest studies of Excedrin.

What is Malabsorption?

Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract) is found to be associated with 652 drugs and 1,095 conditions by eHealthMe. Check the latest studies of Malabsorption.

On Apr, 25, 2026

21,620 people reported to have side effects when taking Excedrin.
Among them, 11 people (0.05%) have Malabsorption.

Among these 11 people:

What is the gender of people who have Malabsorption when taking Excedrin? *

female: 66.67 %
male: 33.33 %

What is the age of people who have Malabsorption when taking Excedrin? *

What are other drugs people take besides Excedrin? *

Benicar: 5 people, 45.45%
Benicar Hct: 5 people, 45.45%
Azor: 2 people, 18.18%
Butalbital And Acetaminophen: 2 people, 18.18%
Prempro: 2 people, 18.18%
Pantoprazole: 2 people, 18.18%
Klor-Con M20: 2 people, 18.18%
Levaquin: 2 people, 18.18%
Xyrem: 1 person, 9.09%
Metformin: 1 person, 9.09%

What are other side effects people have besides Malabsorption? *

Haemorrhoids (a swollen vein or group of veins in the region of the anus): 5 people, 45.45%
Stress And Anxiety: 3 people, 27.27%
Dizziness: 3 people, 27.27%
Gastrointestinal Infection (infection of stomach and intestine): 2 people, 18.18%
Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 2 people, 18.18%
Celiac Disease - Sprue (a disease of the small intestine): 2 people, 18.18%
Constipation: 2 people, 18.18%
Diverticulum Intestinal (a pouch that is attached to the first part of the small intestine): 2 people, 18.18%
Duodenitis (inflammation of the duodenum): 2 people, 18.18%
Gallstones (stone formation by bile component): 2 people, 18.18%

What are the existing conditions these people have? *

High Blood Pressure: 8 people, 72.73%
Infection: 2 people, 18.18%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 9.09%
Multiple Myeloma (cancer of the plasma cells): 1 person, 9.09%
Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Excedrin and have Malabsorption?

- Check whether Malabsorption is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Excedrin:

Excedrin (22,740 reports)

Malabsorption treatments and more:

Malabsorption (8,910 reports)

How severe was Malabsorption and when was it recovered:

Malabsorption in Excedrin

Expand to all the drugs that have ingredients of acetaminophen; aspirin; caffeine:

Malabsorption and drugs with ingredients of acetaminophen; aspirin; caffeine (10 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Excedrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Malabsorption:

Malabsorption (652 drugs)

Browse all the conditions that are associated with Malabsorption:

Malabsorption (1,095 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; aspirin; caffeine (the active ingredients of Excedrin) and Excedrin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.