Excedrin and Maternal exposure during pregnancy - a phase IV clinical study of FDA data

Summary:

Maternal exposure during pregnancy is reported as a side effect among people who take Excedrin (acetaminophen; aspirin; caffeine), especially for people who are 30-39 old, have been taking the drug for 6 - 12 months also take Tylenol, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Maternal exposure during pregnancy when taking Excedrin. It is created by eHealthMe based on reports of 21,620 people who have side effects when taking Excedrin from the FDA, and is updated regularly.

What is Excedrin?

Excedrin has active ingredients of acetaminophen; aspirin; caffeine. It is often used in headache. eHealthMe is studying from 22,740 Excedrin users. Check the latest studies of Excedrin.

What is Maternal exposure during pregnancy?

Maternal exposure during pregnancy (use of substance during pregnancy) is found to be associated with 1,327 drugs and 1,531 conditions by eHealthMe. Check the latest studies of Maternal exposure during pregnancy.

On Aug, 01, 2026

21,620 people reported to have side effects when taking Excedrin.
Among them, 56 people (0.26%) have Maternal exposure during pregnancy.

Could Excedrin cause Maternal exposure during pregnancy?

Among these 56 people:

How long have people been on Excedrin when they have Maternal exposure during pregnancy? *

What is the age of people who have Maternal exposure during pregnancy when taking Excedrin? *

What are other drugs people take besides Excedrin? *

What are other side effects people have besides Maternal exposure during pregnancy? *

Premature Labor: 8 people, 14.29%
Abortion Spontaneous (naturally occurring miscarriage): 7 people, 12.50%
Maternal Exposure Before Pregnancy (use of substance before pregnancy): 7 people, 12.50%
Placenta Praevia (a condition that occurs during pregnancy when the placenta is abnormally placed, and partially or totally covers the cervix): 5 people, 8.93%
Stress And Anxiety: 5 people, 8.93%
Blood Glucose Increased: 4 people, 7.14%
Nausea (feeling of having an urge to vomit): 3 people, 5.36%
Drowsiness: 3 people, 5.36%
Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 3 people, 5.36%
Haemorrhage (bleeding): 3 people, 5.36%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 8 people, 14.29%
Stress And Anxiety: 7 people, 12.50%
Depression: 5 people, 8.93%
Hypersensitivity: 5 people, 8.93%
Nausea (feeling of having an urge to vomit): 5 people, 8.93%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 7.14%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 7.14%
Asthma: 4 people, 7.14%
Birth Control: 4 people, 7.14%
Bone Pain: 4 people, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Excedrin and have Maternal exposure during pregnancy?

- Check whether Maternal exposure during pregnancy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Excedrin:

Excedrin (22,740 reports)

Maternal exposure during pregnancy treatments and more:

Maternal exposure during pregnancy (88,837 reports)

How severe was Maternal exposure during pregnancy and when was it recovered:

Maternal exposure during pregnancy in Excedrin

Expand to all the drugs that have ingredients of acetaminophen; aspirin; caffeine:

Maternal exposure during pregnancy and drugs with ingredients of acetaminophen; aspirin; caffeine

Sub-studies by age:

0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Excedrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Maternal exposure during pregnancy:

Maternal exposure during pregnancy (1,327 drugs)

Browse all the conditions that are associated with Maternal exposure during pregnancy:

Maternal exposure during pregnancy (1,531 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; aspirin; caffeine (the active ingredients of Excedrin) and Excedrin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.