Exelon and Hypertonia - a phase IV clinical study of FDA data

Summary:

Hypertonia is reported as a side effect among people who take Exelon (rivastigmine tartrate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Aricept, and have Parkinson's disease.

The phase IV clinical study analyzes which people have Hypertonia when taking Exelon. It is created by eHealthMe based on reports of 10,864 people who have side effects when taking Exelon from the FDA, and is updated regularly.

What is Exelon?

Exelon has active ingredients of rivastigmine tartrate. It is often used in alzheimer's disease. eHealthMe is studying from 11,060 Exelon users. Check the latest studies of Exelon.

What is Hypertonia?

Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch) is found to be associated with 487 drugs and 695 conditions by eHealthMe. Check the latest studies of Hypertonia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

10,864 people reported to have side effects when taking Exelon.
Among them, 15 people (0.14%) have Hypertonia.

Among these 15 people:

How long have people been on Exelon when they have Hypertonia? *

What is the gender of people who have Hypertonia when taking Exelon? *

female: 66.67 %
male: 33.33 %

What is the age of people who have Hypertonia when taking Exelon? *

What are other drugs people take besides Exelon? *

Aricept: 2 people, 13.33%
Zyprexa: 1 person, 6.67%
Dantrium: 1 person, 6.67%
Memantine Hydrochloride: 1 person, 6.67%
Levothyroxine Sodium: 1 person, 6.67%
Gliclazide: 1 person, 6.67%
Fluoxetine: 1 person, 6.67%
Esomeprazole Magnesium: 1 person, 6.67%
Dyazide: 1 person, 6.67%
Cymbalta: 1 person, 6.67%

What are other side effects people have besides Hypertonia? *

Muscle Rigidity (muscle stiffness): 5 people, 33.33%
Confusional State: 4 people, 26.67%
Agitation (state of anxiety or nervous excitement): 4 people, 26.67%
General Physical Health Deterioration (weak health status): 4 people, 26.67%
Fall: 3 people, 20.00%
Tremor (trembling or shaking movements in one or more parts of your body): 2 people, 13.33%
Fever: 2 people, 13.33%
Dehydration (dryness resulting from the removal of water): 2 people, 13.33%
Masked Facies (mask like facial expression, display little facial expression): 2 people, 13.33%
Speech Impairment (Adult) (inability to speak (adult)): 2 people, 13.33%

What are the existing conditions these people have? *

Parkinson's Disease: 3 people, 20.00%
Vulvovaginal Dryness: 1 person, 6.67%
Type 2 Diabetes: 1 person, 6.67%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 6.67%
Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 1 person, 6.67%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 6.67%
Hallucinations (sensations that appear real but are created by your mind): 1 person, 6.67%
Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 6.67%
Essential Hypertension (primary hypertension): 1 person, 6.67%
Depression: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Exelon and have Hypertonia?

- Check whether Hypertonia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Exelon:

Exelon (11,060 reports)

Hypertonia treatments and more:

Hypertonia (11,073 reports)

Browse all side effects of Exelon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypertonia:

Hypertonia (487 drugs)

Browse all the conditions that are associated with Hypertonia:

Hypertonia (695 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on rivastigmine tartrate (the active ingredients of Exelon) and Exelon (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.