Exforge and Appendicitis - a phase IV clinical study of FDA data

Summary:

Appendicitis is reported as a side effect among people who take Exforge (amlodipine besylate; valsartan), especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years also take Enbrel, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Appendicitis when taking Exforge. It is created by eHealthMe based on reports of 12,942 people who have side effects when taking Exforge from the FDA, and is updated regularly.

What is Exforge?

Exforge has active ingredients of amlodipine besylate; valsartan. It is often used in high blood pressure. eHealthMe is studying from 13,350 Exforge users. Check the latest studies of Exforge.

What is Appendicitis?

Appendicitis (inflammation of the appendix) is found to be associated with 842 drugs and 891 conditions by eHealthMe. Check the latest studies of Appendicitis.

On Apr, 21, 2026

12,942 people reported to have side effects when taking Exforge.
Among them, 19 people (0.15%) have Appendicitis.

Among these 19 people:

How long have people been on Exforge when they have Appendicitis? *

What is the gender of people who have Appendicitis when taking Exforge? *

female: 50 %
male: 50 %

What is the age of people who have Appendicitis when taking Exforge? *

What are other drugs people take besides Exforge? *

What are other side effects people have besides Appendicitis? *

Abdominal Pain: 5 people, 26.32%
The Flu (the flu is caused by an influenza virus): 5 people, 26.32%
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle): 4 people, 21.05%
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs): 4 people, 21.05%
Fever: 4 people, 21.05%
Constipation: 3 people, 15.79%
Pain: 3 people, 15.79%
Upper Respiratory Fungal Infection: 3 people, 15.79%
Tonsillitis (inflammation of tonsil): 3 people, 15.79%
Decreased Immune Responsiveness: 3 people, 15.79%

What are the existing conditions these people have? *

Ankylosing Spondylitis (type of arthritis affecting the spine): 3 people, 15.79%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 15.79%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 10.53%
High Blood Cholesterol: 2 people, 10.53%
Diabetes: 2 people, 10.53%
Dysmenorrhea (painful menstruation): 1 person, 5.26%
Arthropathy: 1 person, 5.26%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 5.26%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 5.26%
Diarrhea: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Exforge and have Appendicitis?

- Check whether Appendicitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Exforge:

Exforge (13,350 reports)

Appendicitis treatments and more:

Appendicitis (11,953 reports)

How severe was Appendicitis and when was it recovered:

Appendicitis in Exforge

Expand to all the drugs that have ingredients of amlodipine besylate; valsartan:

Appendicitis and drugs with ingredients of amlodipine besylate; valsartan

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Exforge:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Appendicitis:

Appendicitis (842 drugs)

Browse all the conditions that are associated with Appendicitis:

Appendicitis (891 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate; valsartan (the active ingredients of Exforge) and Exforge (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.