Exforge and Chd - a phase IV clinical study of FDA data

Summary:

Chd is reported as a side effect among people who take Exforge (amlodipine besylate; valsartan), especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years also take Aspirin, and have Diabetes.

The phase IV clinical study analyzes which people have Chd when taking Exforge. It is created by eHealthMe based on reports of 12,942 people who have side effects when taking Exforge from the FDA, and is updated regularly.

What is Exforge?

Exforge has active ingredients of amlodipine besylate; valsartan. It is often used in high blood pressure. eHealthMe is studying from 13,350 Exforge users. Check the latest studies of Exforge.

What is Chd?

Chd (disease of heart coronary artery) is found to be associated with 2,567 drugs and 2,142 conditions by eHealthMe. Check the latest studies of Chd.



On Oct, 11, 2025

12,942 people reported to have side effects when taking Exforge.
Among them, 58 people (0.45%) have Chd.

Could Exforge cause Chd?

Among these 58 people:

How long have people been on Exforge when they have Chd? *

  • < 1 month: 12.5 %
  • 1 - 6 months: 25.0 %
  • 6 - 12 months: 25.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 37.5 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Chd when taking Exforge? *

  • female: 43.86 %
  • male: 56.14 %

What is the age of people who have Chd when taking Exforge? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 2.27 %
  • 40-49: 9.09 %
  • 50-59: 29.55 %
  • 60+: 59.09 %

What are other drugs people take besides Exforge? *

  1. Aspirin: 12 people, 20.69%
  2. Plavix: 10 people, 17.24%
  3. Avandia: 7 people, 12.07%
  4. Lipitor: 7 people, 12.07%
  5. Lasix: 6 people, 10.34%
  6. Metformin: 6 people, 10.34%
  7. Omeprazole: 6 people, 10.34%
  8. Exforge Hct: 6 people, 10.34%
  9. Hydrochlorothiazide: 5 people, 8.62%
  10. Bystolic: 5 people, 8.62%

What are other side effects people have besides Chd? *

  1. Heart Attack: 14 people, 24.14%
  2. Diabetes: 9 people, 15.52%
  3. Depression: 7 people, 12.07%
  4. Ascites (accumulation of fluid in the abdominal cavity): 7 people, 12.07%
  5. Pleural Effusion (water on the lungs): 7 people, 12.07%
  6. Chest Pain: 7 people, 12.07%
  7. High Blood Cholesterol: 7 people, 12.07%
  8. Acute Myocardial Infarction (acute heart attack): 7 people, 12.07%
  9. Weakness: 7 people, 12.07%
  10. Stable Angina (a constant chest pain): 6 people, 10.34%

What are the existing conditions these people have? *

  1. Diabetes: 12 people, 20.69%
  2. Oedema (fluid collection in tissue): 4 people, 6.90%
  3. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 5.17%
  4. Colitis (inflammation of colon): 3 people, 5.17%
  5. High Blood Cholesterol: 3 people, 5.17%
  6. Type 2 Diabetes: 2 people, 3.45%
  7. Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 3.45%
  8. Bleeding Disorders: 2 people, 3.45%
  9. Cardiac Failure: 2 people, 3.45%
  10. Chest Pain: 2 people, 3.45%

* Approximation only. Some reports may have incomplete information.

Do you take Exforge and have Chd?

- Check whether Chd is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Exforge:

Chd treatments and more:

  • Chd (70,499 reports)

How severe was Chd and when was it recovered:

Expand to all the drugs that have ingredients of amlodipine besylate; valsartan:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Exforge:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Chd:

  • Chd (2,567 drugs)

Browse all the conditions that are associated with Chd:

  • Chd (2,142 conditions)

Drugs similar to Exforge and Chd :


How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate; valsartan (the active ingredients of Exforge) and Exforge (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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