Exforge and Hypercalcaemia - a phase IV clinical study of FDA data

Summary:

Hypercalcaemia is reported as a side effect among people who take Exforge (amlodipine besylate; valsartan), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Rocaltrol, and have Osteoporosis.

The phase IV clinical study analyzes which people have Hypercalcaemia when taking Exforge. It is created by eHealthMe based on reports of 12,942 people who have side effects when taking Exforge from the FDA, and is updated regularly.

What is Exforge?

Exforge has active ingredients of amlodipine besylate; valsartan. It is often used in high blood pressure. eHealthMe is studying from 13,350 Exforge users. Check the latest studies of Exforge.

What is Hypercalcaemia?

Hypercalcaemia (elevated calcium (ca+) level in the blood) is found to be associated with 1,065 drugs and 1,016 conditions by eHealthMe. Check the latest studies of Hypercalcaemia.

On Jul, 08, 2026

12,942 people reported to have side effects when taking Exforge.
Among them, 12 people (0.09%) have Hypercalcaemia.

Among these 12 people:

How long have people been on Exforge when they have Hypercalcaemia? *

What is the gender of people who have Hypercalcaemia when taking Exforge? *

female: 75 %
male: 25 %

What is the age of people who have Hypercalcaemia when taking Exforge? *

What are other drugs people take besides Exforge? *

Rocaltrol: 3 people, 25.00%
Vesicare: 2 people, 16.67%
Folic Acid: 2 people, 16.67%
Donepezil Hydrochloride: 2 people, 16.67%
Enbrel: 2 people, 16.67%
Famotidine: 2 people, 16.67%
Clopidogrel: 1 person, 8.33%
Cordarone: 1 person, 8.33%
Diovan: 1 person, 8.33%
Docetaxel: 1 person, 8.33%

What are other side effects people have besides Hypercalcaemia? *

Acute Kidney Failure: 4 people, 33.33%
Cardiac Failure: 2 people, 16.67%
Rib Fracture: 1 person, 8.33%
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight): 1 person, 8.33%
Arrhythmias (irregular heartbeat): 1 person, 8.33%
Back Pain: 1 person, 8.33%
Blood Creatinine Increased: 1 person, 8.33%
Cardiac Aneurysm (a condition that can occur after a myocardial infarction due to the inadequate resistance of the new scar tissue to the systolic pressure): 1 person, 8.33%
Consciousness - Decreased: 1 person, 8.33%
Constipation: 1 person, 8.33%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 3 people, 25.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 16.67%
Pernicious Anaemia (anaemia due to lack of vitamin b12): 2 people, 16.67%
Parkinson's Disease: 2 people, 16.67%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 2 people, 16.67%
Gastritis (inflammation of stomach): 2 people, 16.67%
Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 2 people, 16.67%
Constipation: 2 people, 16.67%
Pain: 1 person, 8.33%
High Blood Cholesterol: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Exforge and have Hypercalcaemia?

- Check whether Hypercalcaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Exforge:

Exforge (13,350 reports)

Hypercalcaemia treatments and more:

Hypercalcaemia (18,731 reports)

How severe was Hypercalcaemia and when was it recovered:

Hypercalcaemia in Exforge

Expand to all the drugs that have ingredients of amlodipine besylate; valsartan:

Hypercalcaemia and drugs with ingredients of amlodipine besylate; valsartan

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Exforge:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypercalcaemia:

Hypercalcaemia (1,065 drugs)

Browse all the conditions that are associated with Hypercalcaemia:

Hypercalcaemia (1,016 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate; valsartan (the active ingredients of Exforge) and Exforge (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.