Exforge and Injection site reaction - a phase IV clinical study of FDA data

Summary:

Injection site reaction is reported as a side effect among people who take Exforge (amlodipine besylate; valsartan), especially for people who are female, 60+ old, also take Potassium, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Injection site reaction when taking Exforge. It is created by eHealthMe based on reports of 12,942 people who have side effects when taking Exforge from the FDA, and is updated regularly.

What is Exforge?

Exforge has active ingredients of amlodipine besylate; valsartan. It is often used in high blood pressure. eHealthMe is studying from 13,350 Exforge users. Check the latest studies of Exforge.

What is Injection site reaction?

Injection site reaction is found to be associated with 1,120 drugs and 1,076 conditions by eHealthMe. Check the latest studies of Injection site reaction.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

12,942 people reported to have side effects when taking Exforge.
Among them, 17 people (0.13%) have Injection site reaction.

Could Exforge cause Injection site reaction?

Among these 17 people:

What is the gender of people who have Injection site reaction when taking Exforge? *

female: 62.5 %
male: 37.5 %

What is the age of people who have Injection site reaction when taking Exforge? *

What are other drugs people take besides Exforge? *

What are other side effects people have besides Injection site reaction? *

Injection Site Pain: 6 people, 35.29%
Injection Site Induration: 5 people, 29.41%
Weight Decreased: 5 people, 29.41%
Weakness: 5 people, 29.41%
Injection Site Mass: 5 people, 29.41%
Fluid Retention (an abnormal accumulation of fluid in the blood): 5 people, 29.41%
Wheezing (a high-pitched whistling sound made while you breath): 4 people, 23.53%
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 4 people, 23.53%
Oropharyngeal Candidiasis (fungal infection of oropharynx): 4 people, 23.53%
Oesophageal Candidiasis (fungal infection of oesophagus): 4 people, 23.53%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 35.29%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 23.53%
Asthma: 4 people, 23.53%
Sleep Disorder: 3 people, 17.65%
Pustular Psoriasis (raised bumps on the skin that are filled with pus): 3 people, 17.65%
Depression: 3 people, 17.65%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 17.65%
Cardiac Disorder: 2 people, 11.76%
Sapho Syndrome (a disorder involving the skin, bone, and joints): 1 person, 5.88%
Drug Dependence: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Exforge and have Injection site reaction?

- Check whether Injection site reaction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Exforge:

Exforge (13,350 reports)

Injection site reaction treatments and more:

Injection site reaction (66,073 reports)

How severe was Injection site reaction and when was it recovered:

Injection site reaction in Exforge

Expand to all the drugs that have ingredients of amlodipine besylate; valsartan:

Injection site reaction and drugs with ingredients of amlodipine besylate; valsartan (17 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Exforge:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Injection site reaction:

Injection site reaction (1,120 drugs)

Browse all the conditions that are associated with Injection site reaction:

Injection site reaction (1,076 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate; valsartan (the active ingredients of Exforge) and Exforge (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.