Exforge and Warm shock - a phase IV clinical study of FDA data

Summary:

Warm shock is reported as a side effect among people who take Exforge (amlodipine besylate; valsartan), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Imbruvica, and have High blood cholesterol.

The phase IV clinical study analyzes which people have Warm shock when taking Exforge. It is created by eHealthMe based on reports of 12,942 people who have side effects when taking Exforge from the FDA, and is updated regularly.

What is Exforge?

Exforge has active ingredients of amlodipine besylate; valsartan. It is often used in high blood pressure. eHealthMe is studying from 13,350 Exforge users. Check the latest studies of Exforge.

What is Warm shock?

Warm shock (septic shock) is found to be associated with 2,350 drugs and 3,319 conditions by eHealthMe. Check the latest studies of Warm shock.

On Oct, 26, 2025

12,942 people reported to have side effects when taking Exforge.
Among them, 33 people (0.25%) have Warm shock.

Among these 33 people:

How long have people been on Exforge when they have Warm shock? *

What is the gender of people who have Warm shock when taking Exforge? *

female: 48.48 %
male: 51.52 %

What is the age of people who have Warm shock when taking Exforge? *

What are other drugs people take besides Exforge? *

What are other side effects people have besides Warm shock? *

Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 10 people, 30.30%
Pneumonia: 10 people, 30.30%
Fever: 8 people, 24.24%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 6 people, 18.18%
Tumor Lysis Syndrome: 6 people, 18.18%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 6 people, 18.18%
Bone Pain: 6 people, 18.18%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 6 people, 18.18%
Urinary Tract Infection: 4 people, 12.12%
Dyspnea (difficult or laboured breathing): 3 people, 9.09%

What are the existing conditions these people have? *

High Blood Cholesterol: 7 people, 21.21%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 6 people, 18.18%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 6 people, 18.18%
Stress And Anxiety: 6 people, 18.18%
Gastric Ph Decreased: 6 people, 18.18%
Hypokalemia (low potassium): 5 people, 15.15%
Parkinson's Disease: 4 people, 12.12%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 9.09%
Diabetes: 3 people, 9.09%
Pain: 3 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Exforge and have Warm shock?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Exforge:

Exforge (13,350 reports)

Warm shock treatments and more:

Warm shock (51,128 reports)

How severe was Warm shock and when was it recovered:

Warm shock in Exforge

Expand to all the drugs that have ingredients of amlodipine besylate; valsartan:

Warm shock and drugs with ingredients of amlodipine besylate; valsartan (39 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Exforge:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Warm shock:

Warm shock (2,350 drugs)

Browse all the conditions that are associated with Warm shock:

Warm shock (3,319 conditions)

Drugs similar to Exforge and Warm shock :

How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate; valsartan (the active ingredients of Exforge) and Exforge (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.