Exidine and International normalised ratio increased - a phase IV clinical study of FDA data

Summary:

International normalised ratio increased is reported as a side effect among people who take Exidine (chlorhexidine gluconate), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Morphine Sulfate, and have Multiple myeloma.

The phase IV clinical study analyzes which people have International normalised ratio increased when taking Exidine. It is created by eHealthMe based on reports of 17,245 people who have side effects when taking Exidine from the FDA, and is updated regularly.

What is Exidine?

Exidine has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 17,299 Exidine users. Check the latest studies of Exidine.

What is International normalised ratio increased?

International normalised ratio increased is found to be associated with 1,334 drugs and 1,727 conditions by eHealthMe. Check the latest studies of International normalised ratio increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

17,245 people reported to have side effects when taking Exidine.
Among them, 37 people (0.21%) have International normalised ratio increased.

Could Exidine cause International normalised ratio increased?

Among these 37 people:

How long have people been on Exidine when they have International normalised ratio increased? *

What is the gender of people who have International normalised ratio increased when taking Exidine? *

female: 16.22 %
male: 83.78 %

What is the age of people who have International normalised ratio increased when taking Exidine? *

What are other drugs people take besides Exidine? *

What are other side effects people have besides International normalised ratio increased? *

Fever: 27 people, 72.97%
Hypotension (abnormally low blood pressure): 26 people, 70.27%
Dyspnea (difficult or laboured breathing): 26 people, 70.27%
Hypophagia (reduced food intake): 23 people, 62.16%
Stress And Anxiety: 23 people, 62.16%
Injury: 23 people, 62.16%
Osteomyelitis (infection of bone): 23 people, 62.16%
Osteonecrosis Of Jaw (death of bone of jaw): 23 people, 62.16%
Pain: 23 people, 62.16%
Pneumonia: 23 people, 62.16%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 18 people, 48.65%
Neoplasm Malignant (cancer tumour): 5 people, 13.51%
Urination - Excessive Volume: 2 people, 5.41%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 5.41%
Cardiac Failure: 2 people, 5.41%
Rashes (redness): 2 people, 5.41%
Headache (pain in head): 1 person, 2.70%
Arrhythmias (irregular heartbeat): 1 person, 2.70%
Bone Marrow Conditioning Regimen: 1 person, 2.70%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 2.70%

* Approximation only. Some reports may have incomplete information.

Do you take Exidine and have International normalised ratio increased?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Exidine:

Exidine (17,299 reports)

International normalised ratio increased treatments and more:

International normalised ratio increased (40,071 reports)

How severe was International normalised ratio increased and when was it recovered:

International normalised ratio increased in Exidine

Expand to all the drugs that have ingredients of chlorhexidine gluconate:

International normalised ratio increased and drugs with ingredients of chlorhexidine gluconate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Exidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with International normalised ratio increased:

International normalised ratio increased (1,334 drugs)

Browse all the conditions that are associated with International normalised ratio increased:

International normalised ratio increased (1,727 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on chlorhexidine gluconate (the active ingredients of Exidine) and Exidine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.