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Exjade and Cognitive disorder - a phase IV clinical study of FDA data

Summary:

Cognitive disorder is reported as a side effect among people who take Exjade (deferasirox), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Piperacillin, and have Serum ferritin increased.

The phase IV clinical study analyzes which people have Cognitive disorder when taking Exjade. It is created by eHealthMe based on reports of 29,418 people who have side effects when taking Exjade from the FDA, and is updated regularly.

What is Exjade?

Exjade has active ingredients of deferasirox. It is often used in iron overload. eHealthMe is studying from 29,456 Exjade users. Check the latest studies of Exjade.

What is Cognitive disorder?

Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving) is found to be associated with 1,649 drugs and 1,727 conditions by eHealthMe. Check the latest studies of Cognitive disorder.

On Aug, 04, 2026

29,418 people reported to have side effects when taking Exjade.
Among them, 29 people (0.1%) have Cognitive disorder.

Could Exjade cause Cognitive disorder?

Among these 29 people:

How long have people been on Exjade when they have Cognitive disorder? *

  • < 1 month: 77.78 %
  • 1 - 6 months: 11.11 %
  • 6 - 12 months: 11.11 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Cognitive disorder when taking Exjade? *

  • female: 81.48 %
  • male: 18.52 %

What is the age of people who have Cognitive disorder when taking Exjade? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 5 %
  • 50-59: 0.0 %
  • 60+: 95 %

What are other drugs people take besides Exjade? *

  1. Clarithromycin: 9 people, 31.03%
  2. Amoxicillin: 9 people, 31.03%
  3. Piperacillin: 9 people, 31.03%
  4. Acetaminophen: 8 people, 27.59%
  5. Nexium: 6 people, 20.69%
  6. Folic Acid: 5 people, 17.24%
  7. Zocor: 3 people, 10.34%
  8. Imodium: 3 people, 10.34%
  9. Aspirin: 3 people, 10.34%
  10. Paracetamol: 3 people, 10.34%

What are other side effects people have besides Cognitive disorder? *

  1. Confusional State: 15 people, 51.72%
  2. Diarrhea: 13 people, 44.83%
  3. Hypotension (abnormally low blood pressure): 12 people, 41.38%
  4. Fever: 12 people, 41.38%
  5. Dry Mouth: 11 people, 37.93%
  6. Bradycardia (abnormally slow heart action): 11 people, 37.93%
  7. Cell Death: 11 people, 37.93%
  8. Rashes (redness): 11 people, 37.93%
  9. Nausea And Vomiting: 11 people, 37.93%
  10. Anaemia (lack of blood): 11 people, 37.93%

What are the existing conditions these people have? *

  1. Serum Ferritin Increased: 9 people, 31.03%
  2. Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 2 people, 6.90%
  3. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 6.90%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 6.90%
  5. Incontinence (lack of moderation or self-control): 2 people, 6.90%
  6. Tumor: 1 person, 3.45%
  7. Hypersensitivity: 1 person, 3.45%
  8. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 3.45%
  9. Bone Marrow Disorder: 1 person, 3.45%
  10. Breast Cancer Metastatic: 1 person, 3.45%

* Approximation only. Some reports may have incomplete information.

Do you take Exjade and have Cognitive disorder?

- Check whether Cognitive disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Exjade:

Cognitive disorder treatments and more:

How severe was Cognitive disorder and when was it recovered:

Expand to all the drugs that have ingredients of deferasirox:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Exjade:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cognitive disorder:

Browse all the conditions that are associated with Cognitive disorder:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on deferasirox (the active ingredients of Exjade) and Exjade (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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