Exjade and Umbilical hernia - a phase IV clinical study of FDA data
Summary:
Umbilical hernia is reported as a side effect among people who take Exjade (deferasirox), especially for people who are female, 30-39 old, have been taking the drug for 2 - 5 years also take Jadenu, and have Chronic myeloid leukaemia.
The phase IV clinical study analyzes which people have Umbilical hernia when taking Exjade. It is created by eHealthMe based on reports of 29,418 people who have side effects when taking Exjade from the FDA, and is updated regularly.
What is Exjade?
Exjade has active ingredients of deferasirox. It is often used in iron overload. eHealthMe is studying from 29,456 Exjade users. Check the latest studies of Exjade.
What is Umbilical hernia?
Umbilical hernia (an outward bulging (protrusion) of the abdominal lining or part of the abdominal organ(s) through the area around the belly button) is found to be associated with 642 drugs and 676 conditions by eHealthMe. Check the latest studies of Umbilical hernia.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
29,418 people reported to have side effects when taking Exjade.
Among them, 17 people (0.06%) have Umbilical hernia.

Among these 17 people:
How long have people been on Exjade when they have Umbilical hernia? *
- < 1 month: 0.0 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 40 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 60 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Umbilical hernia when taking Exjade? *
- female: 52.94 %
- male: 47.06 %
What is the age of people who have Umbilical hernia when taking Exjade? *
- 0-1: 0.0 %
- 2-9: 46.15 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 46.15 %
- 40-49: 7.69 %
- 50-59: 0.0 %
- 60+: 0.0 %
What are other drugs people take besides Exjade? *
- Tasigna: 3 people, 17.65%
- Jadenu: 3 people, 17.65%
- Zovirax: 1 person, 5.88%
- Vicodin: 1 person, 5.88%
- Solu-Medrol: 1 person, 5.88%
- Rituxan: 1 person, 5.88%
- Revlimid: 1 person, 5.88%
- Mucinex: 1 person, 5.88%
- Levaquin: 1 person, 5.88%
- Lasix: 1 person, 5.88%
What are other side effects people have besides Umbilical hernia? *
- Pain: 10 people, 58.82%
- Serum Ferritin Increased: 8 people, 47.06%
- Ultrasound Doppler Abnormal: 7 people, 41.18%
- Stress And Anxiety: 7 people, 41.18%
- Yellow Skin: 6 people, 35.29%
- Renal Disorder (kidney disease): 6 people, 35.29%
- Haemoglobin Decreased: 6 people, 35.29%
- Paleness (unusual lightness of skin colour): 6 people, 35.29%
- Chest Pain: 5 people, 29.41%
- Pleural Effusion (water on the lungs): 5 people, 29.41%
What are the existing conditions these people have? *
- Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 3 people, 17.65%
- Serum Ferritin Increased: 1 person, 5.88%
- Pneumonia: 1 person, 5.88%
- Pain: 1 person, 5.88%
- Multiple Myeloma (cancer of the plasma cells): 1 person, 5.88%
- Lice Infestation (colonization of lice in head or skin): 1 person, 5.88%
- Haematocrit Decreased: 1 person, 5.88%
- Fever: 1 person, 5.88%
- Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 5.88%
- Aplastic Anemia: 1 person, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Exjade and have Umbilical hernia?
- Check whether Umbilical hernia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Exjade:
- Exjade (29,456 reports)
Umbilical hernia treatments and more:
- Umbilical hernia (6,085 reports)
How severe was Umbilical hernia and when was it recovered:
Expand to all the drugs that have ingredients of deferasirox:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Exjade:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Umbilical hernia:
- Umbilical hernia (642 drugs)
Browse all the conditions that are associated with Umbilical hernia:
- Umbilical hernia (676 conditions)
Related publications that referenced our studies
- Díaz-García JD, Gallegos-Villalobos A, Gonzalez-Espinoza L, Sanchez-Ni?o MD, Villarrubia J, Ortiz A, "Deferasirox nephrotoxicity [mdash] the knowns and unknowns", Nature reviews nephrology, 2014 Oct .
- Riva A, "Comment on: A record number of fatalities in many categories of patients treated with deferasirox: loopholes in regulatory and marketing procedures undermine patient safety and misguide public funds?", Expert opinion on drug safety, 2013 Sep .
- Riva A, "Deferasirox's toxicity", The Lancet, 2013 Jul .
- Kontoghiorghes GJ, "Turning a blind eye to deferasirox's toxicity?", The Lancet, 2013 Apr .
- Kontoghiorghes GJ, "A record number of fatalities in many categories of patients treated with deferasirox: loopholes in regulatory and marketing procedures undermine patient safety and misguide public funds?", Taylor & Francis, 2013 Jan .
- Díaz-García JD, Gallegos-Villalobos A, Gonzalez-Espinoza L, Sanchez-Ni?o MD, Villarrubia J, Ortiz A, "Deferasirox nephrotoxicity [mdash] the knowns and unknowns", Nature reviews nephrology, 2014 Oct .
- Riva A, "Comment on: A record number of fatalities in many categories of patients treated with deferasirox: loopholes in regulatory and marketing procedures undermine patient safety and misguide public funds?", Expert opinion on drug safety, 2013 Sep .
- Riva A, "Deferasirox's toxicity", The Lancet, 2013 Jul .
- Kontoghiorghes GJ, "Turning a blind eye to deferasirox's toxicity?", The Lancet, 2013 Apr .
- Kontoghiorghes GJ, "A record number of fatalities in many categories of patients treated with deferasirox: loopholes in regulatory and marketing procedures undermine patient safety and misguide public funds?", Taylor & Francis, 2013 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on deferasirox (the active ingredients of Exjade) and Exjade (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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