Exondys 51 and Constipation - a phase IV clinical study of FDA data

Summary:

Constipation is reported as a side effect among people who take Exondys 51 (eteplirsen), especially for people who are male, 10-19 old, have been taking the drug for 2 - 5 years also take Deltasone, and have Pain.

The phase IV clinical study analyzes which people have Constipation when taking Exondys 51. It is created by eHealthMe based on reports of 1,598 people who have side effects when taking Exondys 51 from the FDA, and is updated regularly.

What is Exondys 51?

Exondys 51 has active ingredients of eteplirsen. eHealthMe is studying from 1,598 Exondys 51 users. Check the latest studies of Exondys 51.

What is Constipation?

Constipation is found to be associated with 3,004 drugs and 4,618 conditions by eHealthMe. Check the latest studies of Constipation.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

1,598 people reported to have side effects when taking Exondys 51.
Among them, 17 people (1.06%) have Constipation.

Among these 17 people:

How long have people been on Exondys 51 when they have Constipation? *

What is the gender of people who have Constipation when taking Exondys 51? *

female: 0.0 %
male: 100 %

What is the age of people who have Constipation when taking Exondys 51? *

What are other drugs people take besides Exondys 51? *

Prilosec: 4 people, 23.53%
Deltasone: 4 people, 23.53%
Melatonin: 3 people, 17.65%
Lidocaine And Prilocaine: 3 people, 17.65%
Miralax: 3 people, 17.65%
Aspirin: 2 people, 11.76%
Vitamin D3: 2 people, 11.76%
Tylenol: 2 people, 11.76%
Tadalafil: 2 people, 11.76%
Emla: 1 person, 5.88%

What are other side effects people have besides Constipation? *

Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 3 people, 17.65%
Agitation (state of anxiety or nervous excitement): 3 people, 17.65%
Delirium (wild excitement): 3 people, 17.65%
Dehydration (dryness resulting from the removal of water): 3 people, 17.65%
Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 3 people, 17.65%
Cardiac Failure Acute: 3 people, 17.65%
High Blood Pressure: 3 people, 17.65%
Adverse Drug Reaction: 3 people, 17.65%
Urination - Painful: 3 people, 17.65%
Arrhythmias (irregular heartbeat): 2 people, 11.76%

What are the existing conditions these people have? *

Pain: 4 people, 23.53%
Wheezing (a high-pitched whistling sound made while you breath): 3 people, 17.65%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 17.65%
Insomnia (sleeplessness): 2 people, 11.76%
Stress And Anxiety: 1 person, 5.88%
Rickets (softening of bones): 1 person, 5.88%
Local Anaesthesia: 1 person, 5.88%
Fever: 1 person, 5.88%
Ear Pruritus (pruritus or itching is ""the unpleasant skin sensation that frequently provokes scratching"" in ear): 1 person, 5.88%
Ear Pain: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Exondys 51 and have Constipation?

- Check whether Constipation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Exondys 51:

Exondys 51 (1,598 reports)

Constipation treatments and more:

Constipation (337,880 reports)

Browse all side effects of Exondys 51:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Constipation:

Constipation (3,004 drugs)

Browse all the conditions that are associated with Constipation:

Constipation (4,618 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on eteplirsen (the active ingredients of Exondys 51) and Exondys 51 (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.