Extavia and Listless - a phase IV clinical study of FDA data

Summary:

Listless is reported as a side effect among people who take Extavia (interferon beta-1b), especially for people who are female, 40-49 old, also take Cortisone Acetate, and have Depression.

The phase IV clinical study analyzes which people have Listless when taking Extavia. It is created by eHealthMe based on reports of 4,879 people who have side effects when taking Extavia from the FDA, and is updated regularly.

What is Extavia?

Extavia has active ingredients of interferon beta-1b. It is often used in multiple sclerosis. eHealthMe is studying from 4,888 Extavia users. Check the latest studies of Extavia.

What is Listless?

Listless (lack of interest, energy, or spirit) is found to be associated with 458 drugs and 653 conditions by eHealthMe. Check the latest studies of Listless.

On Jul, 28, 2026

4,879 people reported to have side effects when taking Extavia.
Among them, 12 people (0.25%) have Listless.

Among these 12 people:

What is the gender of people who have Listless when taking Extavia? *

female: 80 %
male: 20 %

What is the age of people who have Listless when taking Extavia? *

What are other drugs people take besides Extavia? *

Wellbutrin: 2 people, 16.67%
Lyrica: 2 people, 16.67%
Cortisone Acetate: 2 people, 16.67%
Medroxyprogesterone Acetate: 1 person, 8.33%
Citalopram Hydrobromide: 1 person, 8.33%

What are other side effects people have besides Listless? *

Headache (pain in head): 8 people, 66.67%
Fatigue (feeling of tiredness): 7 people, 58.33%
Influenza Like Illness: 6 people, 50.00%
Injection Site Pruritus (severe itching at injection site): 5 people, 41.67%
Injection Site Erythema (redness at injection site): 4 people, 33.33%
Body Temperature Increased: 4 people, 33.33%
Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 33.33%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 3 people, 25.00%
Lymphoedema (localized fluid retention and tissue swelling): 3 people, 25.00%
Hypersensitivity: 3 people, 25.00%

What are the existing conditions these people have? *

Trigeminal Neuralgia (a painful condition of the nerve responsible for most facial sensation): 2 people, 16.67%
Thyroid Diseases: 2 people, 16.67%
Fatigue (feeling of tiredness): 2 people, 16.67%
Depression: 2 people, 16.67%
Birth Control: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Extavia and have Listless?

- Check whether Listless is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Extavia:

Extavia (4,888 reports)

Listless treatments and more:

Listless (4,524 reports)

Browse all side effects of Extavia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Listless:

Listless (458 drugs)

Browse all the conditions that are associated with Listless:

Listless (653 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on interferon beta-1b (the active ingredients of Extavia) and Extavia (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.