Extraneal and Angina pectoris aggravated - a phase IV clinical study of FDA data

Summary:

Angina pectoris aggravated is reported as a side effect among people who take Extraneal (icodextrin), especially for people who are male, 60+ old, have been taking the drug for 1 - 2 years also take Dianeal 137 W/ Dextrose 2.5% In Plastic Container, and have Chronic kidney disease.

The phase IV clinical study analyzes which people have Angina pectoris aggravated when taking Extraneal. It is created by eHealthMe based on reports of 32,991 people who have side effects when taking Extraneal from the FDA, and is updated regularly.

What is Extraneal?

Extraneal has active ingredients of icodextrin. eHealthMe is studying from 32,994 Extraneal users. Check the latest studies of Extraneal.

What is Angina pectoris aggravated?

Angina pectoris aggravated (chest pain due to ischemia of the heart muscle) is found to be associated with 1,387 drugs and 655 conditions by eHealthMe. Check the latest studies of Angina pectoris aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

32,991 people reported to have side effects when taking Extraneal.
Among them, 36 people (0.11%) have Angina pectoris aggravated.

Could Extraneal cause Angina pectoris aggravated?

Among these 36 people:

How long have people been on Extraneal when they have Angina pectoris aggravated? *

What is the gender of people who have Angina pectoris aggravated when taking Extraneal? *

female: 31.43 %
male: 68.57 %

What is the age of people who have Angina pectoris aggravated when taking Extraneal? *

What are other drugs people take besides Extraneal? *

Voltaren: 1 person, 2.78%
Tegretol: 1 person, 2.78%
Tacrolimus: 1 person, 2.78%
Renagel: 1 person, 2.78%
Prednisolone: 1 person, 2.78%
Polaramine: 1 person, 2.78%
Mycophenolate Mofetil: 1 person, 2.78%
Micardis: 1 person, 2.78%
Insulin: 1 person, 2.78%
Dianeal 137 W/ Dextrose 2.5% In Plastic Container: 1 person, 2.78%

What are other side effects people have besides Angina pectoris aggravated? *

Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 8.33%
Heart Attack: 3 people, 8.33%
Dyspnea (difficult or laboured breathing): 2 people, 5.56%
Constipation: 2 people, 5.56%
Cardiac Disorder: 2 people, 5.56%
Coronary Artery Occlusion (complete obstruction of blood flow in a coronary artery): 2 people, 5.56%
Device Occlusion: 1 person, 2.78%
Dermatitis Acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis): 1 person, 2.78%
Dehydration (dryness resulting from the removal of water): 1 person, 2.78%
Coronary Artery Stenosis (narrowing of coronary artery): 1 person, 2.78%

What are the existing conditions these people have? *

Chronic Kidney Disease: 7 people, 19.44%
Chronic Renal Failure (kidney failure): 2 people, 5.56%
Acute Kidney Failure: 2 people, 5.56%
High Blood Pressure: 1 person, 2.78%
Diabetic Nephropathy (diabetic kidney disease): 1 person, 2.78%

* Approximation only. Some reports may have incomplete information.

Do you take Extraneal and have Angina pectoris aggravated?

- Check whether Angina pectoris aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Extraneal:

Extraneal (32,994 reports)

Browse all side effects of Extraneal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Angina pectoris aggravated:

Angina pectoris aggravated (1,387 drugs)

Browse all the conditions that are associated with Angina pectoris aggravated:

Angina pectoris aggravated (655 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on icodextrin (the active ingredients of Extraneal) and Extraneal (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.