Extraneal and Application site irritation - a phase IV clinical study of FDA data
Summary:
Application site irritation is reported as a side effect among people who take Extraneal (icodextrin), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months.
The phase IV clinical study analyzes which people have Application site irritation when taking Extraneal. It is created by eHealthMe based on reports of 32,991 people who have side effects when taking Extraneal from the FDA, and is updated regularly.
What is Extraneal?
Extraneal has active ingredients of icodextrin. eHealthMe is studying from 32,994 Extraneal users. Check the latest studies of Extraneal.
What is Application site irritation?
Application site irritation is found to be associated with 390 drugs and 700 conditions by eHealthMe. Check the latest studies of Application site irritation.
32,991 people reported to have side effects when taking Extraneal.
Among them, 16 people (0.05%) have Application site irritation.

Among these 16 people:
How long have people been on Extraneal when they have Application site irritation? *
- < 1 month: 0.0 %
- 1 - 6 months: 100 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Application site irritation when taking Extraneal? *
- female: 50 %
- male: 50 %
What is the age of people who have Application site irritation when taking Extraneal? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 0.0 %
- 50-59: 33.33 %
- 60+: 66.67 %
What are other side effects people have besides Application site irritation? *
- Pneumonia: 2 people, 12.50%
- Device Related Infection: 2 people, 12.50%
- Weight Decreased: 1 person, 6.25%
- Traumatic Haemorrhage (a bleeding due to trauma): 1 person, 6.25%
- Skin Wound: 1 person, 6.25%
- Peripheral Swelling: 1 person, 6.25%
- Malaise (a feeling of general discomfort or uneasiness): 1 person, 6.25%
- Itching: 1 person, 6.25%
- Dehydration (dryness resulting from the removal of water): 1 person, 6.25%
- Application Site Reaction: 1 person, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Extraneal and have Application site irritation?
- Check whether Application site irritation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Extraneal:
- Extraneal (32,994 reports)
Application site irritation treatments and more:
- Application site irritation (12,156 reports)
How severe was Application site irritation and when was it recovered:
Expand to all the drugs that have ingredients of icodextrin:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Extraneal:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Application site irritation:
- Application site irritation (390 drugs)
Browse all the conditions that are associated with Application site irritation:
- Application site irritation (700 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on icodextrin (the active ingredients of Extraneal) and Extraneal (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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