Extraneal and Cachexia - a phase IV clinical study of FDA data

Summary:

Cachexia is reported as a side effect among people who take Extraneal (icodextrin), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Physiosol In Plastic Container, and have Acute kidney failure.

The phase IV clinical study analyzes which people have Cachexia when taking Extraneal. It is created by eHealthMe based on reports of 32,991 people who have side effects when taking Extraneal from the FDA, and is updated regularly.

What is Extraneal?

Extraneal has active ingredients of icodextrin. eHealthMe is studying from 32,994 Extraneal users. Check the latest studies of Extraneal.

What is Cachexia?

Cachexia (loss of weight) is found to be associated with 666 drugs and 1,201 conditions by eHealthMe. Check the latest studies of Cachexia.

On Jun, 17, 2026

32,991 people reported to have side effects when taking Extraneal.
Among them, 25 people (0.08%) have Cachexia.

Among these 25 people:

How long have people been on Extraneal when they have Cachexia? *

What is the gender of people who have Cachexia when taking Extraneal? *

female: 32 %
male: 68 %

What is the age of people who have Cachexia when taking Extraneal? *

What are other drugs people take besides Extraneal? *

Physiosol In Plastic Container: 6 people, 24.00%
Metoprolol Succinate: 5 people, 20.00%
Renagel: 5 people, 20.00%
Calcitriol: 3 people, 12.00%
Doxazosin Mesylate: 3 people, 12.00%
Lisinopril: 3 people, 12.00%
Micardis: 3 people, 12.00%
Amlodipine: 3 people, 12.00%
Aranesp: 2 people, 8.00%
Simvastatin: 2 people, 8.00%

What are other side effects people have besides Cachexia? *

General Physical Health Deterioration (weak health status): 5 people, 20.00%
Death: 5 people, 20.00%
Infection: 4 people, 16.00%
Hypokalemia (low potassium): 4 people, 16.00%
Sclerosing Encapsulating Peritonitis (thick peritoneal membranes): 4 people, 16.00%
Rashes (redness): 4 people, 16.00%
Metabolic Disorder (an abnormal function and pattern of body fat. insulin resistance refers to the diminished ability of cells to respond to the action of insulin in promoting the transport of the sugar glucose, from blood into muscles and other tissues): 3 people, 12.00%
Weakness: 3 people, 12.00%
Dehydration (dryness resulting from the removal of water): 3 people, 12.00%
Peritonitis Bacterial (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs by bacterial): 3 people, 12.00%

What are the existing conditions these people have? *

Acute Kidney Failure: 4 people, 16.00%
Chronic Renal Failure (kidney failure): 2 people, 8.00%
Chronic Kidney Disease: 2 people, 8.00%
Pain: 1 person, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Extraneal and have Cachexia?

- Check whether Cachexia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Extraneal:

Extraneal (32,994 reports)

Cachexia treatments and more:

Cachexia (7,763 reports)

Browse all side effects of Extraneal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cachexia:

Cachexia (666 drugs)

Browse all the conditions that are associated with Cachexia:

Cachexia (1,201 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on icodextrin (the active ingredients of Extraneal) and Extraneal (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.