Extraneal and Cardiac death - a phase IV clinical study of FDA data

Summary:

Cardiac death is reported as a side effect among people who take Extraneal (icodextrin), especially for people who are male, 60+ old, have been taking the drug for 5 - 10 years also take Crestor, and have Chronic renal failure.

The study is created by eHealthMe based on reports of 32,991 people who have side effects when taking Extraneal from the FDA, and is updated regularly.

What is Extraneal?

Extraneal has active ingredients of icodextrin. eHealthMe is studying from 32,994 Extraneal users. Check the latest studies of Extraneal.

On Jul, 14, 2026

32,991 people reported to have side effects when taking Extraneal.
Among them, 11 people (0.03%) died.

Among these 11 people:

How long have people been on Extraneal when they died? *

What is the gender of people who died when taking Extraneal? *

female: 27.27 %
male: 72.73 %

What is the age of people who died when taking Extraneal? *

What are other drugs people take besides Extraneal? *

Aranesp: 2 people, 18.18%
Physiosol In Plastic Container: 2 people, 18.18%
Crestor: 2 people, 18.18%
Zemplar: 1 person, 9.09%
Loniten: 1 person, 9.09%
Amlodipine: 1 person, 9.09%
Cardura: 1 person, 9.09%
Cordarone: 1 person, 9.09%
Diovan: 1 person, 9.09%
Mircera: 1 person, 9.09%

What are other side effects people have before they died? *

Sepsis (a severe blood infection that can lead to organ failure and death): 1 person, 9.09%
Loss Of Consciousness: 1 person, 9.09%
Heart Attack: 1 person, 9.09%

What are the existing conditions these people have? *

Renal Insufficiency (insufficient excretion of wastes by the kidneys): 1 person, 9.09%
Glomerulonephritis Chronic (long lasting group of conditions that affect parts of the kidneys called glomeruli): 1 person, 9.09%
Chronic Renal Failure (kidney failure): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Extraneal:

Extraneal (32,994 reports)

Expand to all the drugs that have ingredients of icodextrin:

Cardiac death and drugs with ingredients of icodextrin

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Extraneal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cardiac death:

Cardiac death (163 drugs)

Browse all the conditions that are associated with Cardiac death:

Cardiac death (223 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on icodextrin (the active ingredients of Extraneal) and Extraneal (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.