Eylea and Blind - a phase IV clinical study of FDA data

Summary:

Blind is reported as a side effect among people who take Eylea (aflibercept), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lucentis, and have Age-related macular degeneration.

The phase IV clinical study analyzes which people have Blind when taking Eylea. It is created by eHealthMe based on reports of 27,819 people who have side effects when taking Eylea from the FDA, and is updated regularly.

What is Eylea?

Eylea has active ingredients of aflibercept. It is often used in macular degeneration. eHealthMe is studying from 27,868 Eylea users. Check the latest studies of Eylea.

What is Blind?

Blind is found to be associated with 2,442 drugs and 1,951 conditions by eHealthMe. Check the latest studies of Blind.



On Sep, 22, 2025

27,819 people reported to have side effects when taking Eylea.
Among them, 1,532 people (5.51%) have Blind.

Could Eylea cause Blind?

Among these 1,532 people:

How long have people been on Eylea when they have Blind? *

  • < 1 month: 82.06 %
  • 1 - 6 months: 4.07 %
  • 6 - 12 months: 4.31 %
  • 1 - 2 years: 5.26 %
  • 2 - 5 years: 3.59 %
  • 5 - 10 years: 0.72 %
  • 10+ years: 0.0 %

What is the gender of people who have Blind when taking Eylea? *

  • female: 60.8 %
  • male: 39.2 %

What is the age of people who have Blind when taking Eylea? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.82 %
  • 30-39: 0.0 %
  • 40-49: 2.87 %
  • 50-59: 11.07 %
  • 60+: 85.25 %

What are other drugs people take besides Eylea? *

  1. Lucentis: 236 people, 15.40%
  2. Avastin: 93 people, 6.07%
  3. Beovu: 26 people, 1.70%
  4. Amlodipine: 23 people, 1.50%
  5. Betadine: 22 people, 1.44%
  6. Metformin: 21 people, 1.37%
  7. Calcium: 14 people, 0.91%
  8. Vabysmo: 13 people, 0.85%
  9. Insulin: 11 people, 0.72%
  10. Simvastatin: 10 people, 0.65%

What are other side effects people have besides Blind? *

  1. Visual Impairment: 278 people, 18.15%
  2. Endophthalmitis (inflammation of the internal coats of the eye): 274 people, 17.89%
  3. Eye Pain: 138 people, 9.01%
  4. Intraocular Pressure Increased: 106 people, 6.92%
  5. Vision Blurred: 104 people, 6.79%
  6. Eye Inflammation: 95 people, 6.20%
  7. Drug Ineffective: 75 people, 4.90%
  8. Eye Haemorrhage (bleeding in the eye): 72 people, 4.70%
  9. Vitritis (inflammation of the vitreous humour of the eye): 67 people, 4.37%
  10. Vitreous Floaters (spots before the eyes): 65 people, 4.24%

What are the existing conditions these people have? *

  1. Age-Related Macular Degeneration: 209 people, 13.64%
  2. Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 195 people, 12.73%
  3. Retinal Vessel Occlusion (a blockage in one of the small arteries): 86 people, 5.61%
  4. Choroidal Neovascularisation (creation of new blood vessels in vascular layer of eye): 72 people, 4.70%
  5. Macular Oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken): 40 people, 2.61%
  6. Diabetic Retinopathy (damage to the retina caused by complications of diabetes): 36 people, 2.35%
  7. High Blood Pressure: 25 people, 1.63%
  8. Pain: 16 people, 1.04%
  9. Asthma: 15 people, 0.98%
  10. Glaucoma (increased fluid pressure in the eye with vision loss): 10 people, 0.65%

* Approximation only. Some reports may have incomplete information.

Do you take Eylea and have Blind?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Eylea:

Blind treatments and more:

How severe was Blind and when was it recovered:

Expand to all the drugs that have ingredients of aflibercept:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Eylea side effects:

Browse all side effects of Eylea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Blind:

Browse all the drugs that are associated with Blind:

Common conditions associated with Blind:

Browse all the conditions that are associated with Blind:

  • Blind (1,951 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on aflibercept (the active ingredients of Eylea) and Eylea (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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